{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:03:00Z","timestamp":1791464580363,"version":"4.3.4"},"reference-count":13,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,9,28]]},"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1136\/bcr-2026-272951","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:45:18Z","timestamp":1791463518000},"page":"e272951","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Transient abnormal myelopoiesis in Down syndrome with normal phenotype: diagnostic challenges"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7715-3849","authenticated-orcid":false,"given":"Ram","family":"Prabu","sequence":"first","affiliation":[{"name":"Pathology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthy","family":"Raman","sequence":"additional","affiliation":[{"name":"Pathology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0971-0055","authenticated-orcid":false,"given":"Karthikeyan","family":"Kadirvel","sequence":"additional","affiliation":[{"name":"Pathology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5096-1406","authenticated-orcid":false,"given":"Debdatta","family":"Basu","sequence":"additional","affiliation":[{"name":"Pathology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,10,8]]},"reference":[{"key":"2026100805451178000_19.10.e272951.1","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2025.1604803","article-title":"Case Report: Transient myeloproliferative disorder with trisomy 21 in blast cells","volume":"13","author":"Zacny","year":"2025","journal-title":"Front Pediatr"},{"key":"2026100805451178000_19.10.e272951.2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01613-1"},{"key":"2026100805451178000_19.10.e272951.3","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32729"},{"key":"2026100805451178000_19.10.e272951.4","doi-asserted-by":"publisher","DOI":"10.14740\/jh306w"},{"key":"2026100805451178000_19.10.e272951.5","doi-asserted-by":"crossref","first-page":"283","DOI":"10.32677\/IJCH.2020.v07.i06.011","article-title":"Transient abnormal myelopoiesis at birth in an infant with Down syndrome: A unique entity","volume":"7","author":"Vechangi","year":"2020","journal-title":"Indian J Child Health"},{"key":"2026100805451178000_19.10.e272951.6","article-title":"Transient abnormal myelopoiesis without constitutional Down syndrome","volume":"9","author":"Kairiene","year":"2019","journal-title":"J Pediatr Neonatal Individ Med"},{"key":"2026100805451178000_19.10.e272951.7","article-title":"Clinical characterization and genetic analysis of transient abnormal myelopoiesis without the Down syndrome phenotype","volume":"42","author":"Cai","year":"2025","journal-title":"Mol Genet Metab Rep"},{"key":"2026100805451178000_19.10.e272951.8","doi-asserted-by":"crossref","DOI":"10.1186\/s12884-022-05139-3","article-title":"Application of chromosome microarray analysis and karyotyping in diagnostic assessment of abnormal Down syndrome screening results","volume":"22","author":"Kang","year":"2022","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026100805451178000_19.10.e272951.9","unstructured":"Leshin L . How to diagnose mosaic Down syndrome in international mosaic Down syndrome association. n.d. Available: https:\/\/www.imdsa.org\/mosaic-down-syndromeInternational"},{"key":"2026100805451178000_19.10.e272951.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2024.104382"},{"key":"2026100805451178000_19.10.e272951.11","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-016-0338-x"},{"key":"2026100805451178000_19.10.e272951.12","article-title":"Acute Megakaryoblastic Leukemia with Trisomy 21 and Tetrasomy 21 Clones in a Phenotypically Normal Child with Mosaic Trisomy 21","volume":"2020","author":"Won","year":"2020","journal-title":"Case Rep Pediatr"},{"key":"2026100805451178000_19.10.e272951.13","article-title":"Transient Abnormal Myelopoeisis and Mosaic Down Syndrome in a Phenotypically Normal Newborn","volume":"7","author":"Prudowsky","year":"2020","journal-title":"Children (Basel)"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2026-272951","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:45:20Z","timestamp":1791463520000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2026-272951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":13,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10,8]]},"published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1136\/bcr-2026-272951"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2026-272951","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]}}}