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Histopathological examination revealed a cystic cavity lined by odontogenic epithelium with ameloblast-like basal cells, polarity reversal, stellate reticulum-like zones, ghost cells and foci of mineralised dental tissue consistent with a diagnosis of archegonous cystic odontoma. Postoperative recovery was unremarkable and follow-up at 18 months confirmed complete bony remodelling with no clinical or radiographic evidence of recurrence. This case highlights a diagnostically challenging odontogenic lesion whose nosological position within the broader primordial odontogenic spectrum continues to generate debate and reinforces the need to correlate clinical, radiographic and histopathological data before reaching a definitive diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2026-273021","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:50:16Z","timestamp":1787313016000},"page":"e273021","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Archegonous cystic odontoma: expanding the spectrum of hybrid odontogenic lesions"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9076-0021","authenticated-orcid":false,"given":"Gayatri","family":"Kulkarni","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Surgery, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2046-3058","authenticated-orcid":false,"given":"Somakshi","family":"Pise","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archit","family":"Dhawan","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankita","family":"Chugh","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gheena","family":"S","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Microbiology and Pathology, Saveetha Institute of Medical and Technical Sciences (Deemed to be University) Saveetha Dental College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026082105201879000_19.8.e273021.1","first-page":"872","article-title":"Prevalence of odontogenic tumors in a Brazilian population: A 12-year study","volume":"47","author":"Fernandes","year":"2018","journal-title":"J Oral Pathol Med"},{"key":"2026082105201879000_19.8.e273021.2","first-page":"338","article-title":"Compound odontoma\u2014Diagnosis and treatment: A case report","volume":"53","author":"Amailuk","year":"2008","journal-title":"Aust Dent J"},{"key":"2026082105201879000_19.8.e273021.3","unstructured":"Regezi JA , Sciubba JJ , Jordan RCK . 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