{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:49:49Z","timestamp":1785761389925,"version":"3.56.0"},"reference-count":10,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,7,22]]},"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>Condyloma acuminata is an uncommon epithelial proliferative and infiltrative growth associated with human papillomavirus (HPV) subtypes 6 and 11. Giant condyloma acuminata is a more aggressive variant characterised by extensive growth, anatomical disfigurement, psychosocial morbidity and a high recurrence rate. Extragenital involvement in an immunocompetent individual is uncommonly reported in the literature. We report a case of an immunocompetent young woman who developed a rapidly progressive verrucous growth involving the vulva, lower vagina, perianal region and also extragenital sites (inframammary fold and axilla). Pelvic MRI demonstrated a large exophytic lesion without underlying stromal involvement. Complete surgical excision with histopathological confirmation demonstrated condyloma acuminata with low-risk HPV type 11. Early recurrence occurred within 3\u2009months, which was managed by topical medication. This case highlights the importance of clinical examination, the role of MRI followed by surgical excision with long-term follow-up even in immunocompetent patients.<\/jats:p>","DOI":"10.1136\/bcr-2026-273280","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:05:21Z","timestamp":1785758721000},"page":"e273280","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Giant anogenital condyloma acuminata with extragenital involvement in an immunocompetent host"],"prefix":"10.1136","volume":"19","author":[{"given":"Himanshi","family":"Bindal","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, AIIMS Bathinda, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lajya","family":"Devi","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, AIIMS Bathinda, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neena","family":"Singh","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, AIIMS Bathinda, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"2026080305051342000_19.8.e273280.1","article-title":"Human papilloma virus: A review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers","volume":"35","author":"Soheili","year":"2021","journal-title":"Med J Islam Repub Iran"},{"key":"2026080305051342000_19.8.e273280.2","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9919446","article-title":"Giant Condyloma Acuminata (Buschke-Lowenstein Tumor): Review of an Unusual Disease and Difficult to Manage","volume":"2021","author":"Nieves-Condoy","year":"2021","journal-title":"Infect Dis Obstet Gynecol"},{"key":"2026080305051342000_19.8.e273280.3","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.2147\/CCID.S426851","article-title":"The Effectiveness of Chemical Cautery and Electrosurgery on Anogenital Wart: Systematic Review","volume":"16","author":"Mawardi","year":"2023","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"2026080305051342000_19.8.e273280.4","doi-asserted-by":"crossref","first-page":"4638","DOI":"10.1097\/MS9.0000000000001102","article-title":"Giant condyloma acuminatum surgical management: a case report and literature review","volume":"85","author":"Al-Ghamdi","year":"2023","journal-title":"Ann Med Surg (Lond)"},{"key":"2026080305051342000_19.8.e273280.5","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.18203\/2320-1770.ijrcog20222333","article-title":"A rare case of giant condyloma acuminata during pregnancy","volume":"11","author":"Choudhary","year":"2022","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"2026080305051342000_19.8.e273280.6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02052606"},{"key":"2026080305051342000_19.8.e273280.7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1055\/s-0035-1568145","article-title":"Complications Following Anorectal Surgery","volume":"29","author":"Kunitake","year":"2016","journal-title":"Clin Colon Rectal Surg"},{"key":"2026080305051342000_19.8.e273280.8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.5152\/dir.2018.17499","article-title":"MRI evaluation of anal and perianal diseases","volume":"25","author":"Balc\u0131","year":"2019","journal-title":"Diagn Interv Radiol"},{"key":"2026080305051342000_19.8.e273280.9","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1016\/j.radcr.2023.05.076","article-title":"CT imaging of condyloma acuminata","volume":"18","author":"Patel","year":"2023","journal-title":"Radiol Case Rep"},{"key":"2026080305051342000_19.8.e273280.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30298-3"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2026-273280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:05:23Z","timestamp":1785758723000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2026-273280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,8,3]]},"published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1136\/bcr-2026-273280"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2026-273280","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]}}}