{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:08:44Z","timestamp":1789736924412,"version":"4.0.1"},"reference-count":16,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,9,1]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>Malakoplakia is a rare granulomatous disease that most frequently affects the genitourinary tract. Its presentation in the colon as a mass lesion is exceptional and poses a significant diagnostic challenge as it closely mimics malignancy on imaging. This case report details the CT and MRI findings of descending colonic malakoplakia in a woman in her 60s with diabetes. The diagnosis was confirmed histopathologically by the presence of Michaelis-Gutmann bodies. The patient was successfully treated with fluoroquinolone antibiotics, which led to near-complete radiological and endoscopic resolution of the lesion after 2 years. This case report demonstrates that imaging may raise clinical suspicion of the disease and guide biopsy and follow-up. However, histological diagnosis remains essential before a decision is made regarding non-surgical management.<\/jats:p>","DOI":"10.1136\/bcr-2026-273798","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:00:21Z","timestamp":1789736421000},"page":"e273798","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Malakoplakia mimicking a colonic tumour: imaging findings, non-surgical management and follow up"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4941-0599","authenticated-orcid":false,"given":"Qitong","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"},{"name":"Biomedical Innovation Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"},{"name":"Biomedical Innovation Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zerong","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"},{"name":"Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0970-4823","authenticated-orcid":false,"given":"Peiyi","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"},{"name":"Biomedical Innovation Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"2026091806001307000_19.9.e273798.1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.57.664.95"},{"key":"2026091806001307000_19.9.e273798.2","doi-asserted-by":"crossref","DOI":"10.1186\/s13000-020-01013-y","article-title":"Malakoplakia of the gastrointestinal tract: clinicopathologic analysis of 23 cases","volume":"15","author":"Lee","year":"2020","journal-title":"Diagn Pathol"},{"key":"2026091806001307000_19.9.e273798.3","first-page":"136","article-title":"Malakoplakia of the stomach. 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