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We report the case of a man in his 50s with NF-DLD complicated by non-small cell lung cancer with mediastinal invasion. Although the clinical course was complicated by radiation pneumonitis and bacterial pneumonia, the patient achieved a complete response following multidisciplinary treatment, which has been sustained for 10 years. This case highlights a rare but clinically significant presentation with a favourable long-term outcome.<\/jats:p>","DOI":"10.1136\/bcr-2026-274527","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:35:40Z","timestamp":1784640940000},"page":"e274527","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Long-term survival of lung cancer despite neurofibromatosis type 1-associated diffuse lung disease"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7442-0086","authenticated-orcid":false,"given":"Tomoyuki","family":"Ogata","sequence":"first","affiliation":[{"name":"Pulmonology, JA Toride Sogo Iryo Center, Toride, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, JA Toride Medical Center, Toride, 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