{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:56:55Z","timestamp":1791219415182,"version":"4.1.0"},"reference-count":9,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,9,13]]},"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>Adrenal gland metastasis from papillary thyroid carcinoma (PTC) is a rare and diagnostically challenging event. Approximately 15 cases of adrenal involvement have been published to date. We report a man in his 70s with previously treated PTC (pT2N1bMx) who re-presented with right cervical lymph node recurrence and a right adrenal mass measuring 5.7\u00d76.5\u2009cm detected on staging cross-sectional imaging. A CT-guided biopsy confirmed metastatic PTC. We performed staged surgery \u2014 right cervical lymph node dissection followed by open right adrenalectomy 4\u2009weeks later. Serum thyroglobulin fell from &gt;500\u2009ng\/mL preoperatively to &lt;1\u2009ng\/mL at 6\u2009months, with no evidence of disease on CT of the neck, chest and abdomen. This case illustrates the possibility of synchronous locoregional and adrenal recurrence in PTC and highlights that cross-sectional imaging of the abdomen is indicated when thyroglobulin is markedly elevated, as recommended by current guidelines.<\/jats:p>","DOI":"10.1136\/bcr-2026-274619","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:10:25Z","timestamp":1791216625000},"page":"e274619","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Adrenal metastasis from papillary thyroid cancer: staged surgical resection"],"prefix":"10.1136","volume":"19","author":[{"given":"Dhalapathy","family":"Sadacharan","sequence":"first","affiliation":[{"name":"Endocrine Surgery, Madras Medical College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abinaya","family":"Venkateswaran","sequence":"additional","affiliation":[{"name":"Madras Medical College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swaminathan","family":"Kalyanasundaram","sequence":"additional","affiliation":[{"name":"Madras Medical College and Government General Hospital, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6915-5639","authenticated-orcid":false,"given":"Shriraam","family":"Mahadevan","sequence":"additional","affiliation":[{"name":"Endocrinology Dept, Sri Ramachandra Institute of Higher Education and Research, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"2026100509101426000_19.10.e274619.1","doi-asserted-by":"crossref","DOI":"10.3332\/ecancer.2025.1956","article-title":"Region-wise pattern of demographic, clinicopathological and treatment profile of thyroid cancers from 96 hospital-based cancer registries in India","volume":"19","author":"Mathew","year":"2025","journal-title":"Ecancermedicalscience"},{"key":"2026100509101426000_19.10.e274619.2","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13071625","article-title":"Site-Specific Metastasis and Survival in Papillary Thyroid Cancer: The Importance of Brain and Multi-Organ Disease","volume":"13","author":"Toraih","year":"2021","journal-title":"Cancers (Basel)"},{"key":"2026100509101426000_19.10.e274619.3","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1089\/thy.2013.0065","article-title":"Papillary thyroid cancer with bilateral adrenal metastases","volume":"23","author":"Batawil","year":"2013","journal-title":"Thyroid"},{"key":"2026100509101426000_19.10.e274619.4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.12970\/2310-9971.2015.03.01.3","article-title":"Adrenal Metastases from Thyroid Cancers: Three Personal Cases and Literature Review","volume":"3","author":"Chentli","year":"2015","journal-title":"J Endocrinol Diabetes Mellit"},{"key":"2026100509101426000_19.10.e274619.5","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1245\/s10434-014-4058-y","article-title":"Rare metastases of well-differentiated thyroid cancers: a systematic review","volume":"22","author":"Madani","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"2026100509101426000_19.10.e274619.6","first-page":"221","article-title":"Papillary Thyroid Carcinoma Metastases Presenting as Ipsilateral Adrenal Mass and Renal Cyst","volume":"3","author":"Ginzburg","year":"2015","journal-title":"Urol Case Rep"},{"key":"2026100509101426000_19.10.e274619.7","doi-asserted-by":"publisher","DOI":"10.1177\/10507256251363120"},{"key":"2026100509101426000_19.10.e274619.8","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.13395"},{"key":"2026100509101426000_19.10.e274619.9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s12022-015-9410-7","article-title":"Unusual Thyroid Carcinoma Metastases: a Case Series and Literature Review","volume":"27","author":"Farina","year":"2016","journal-title":"Endocr Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2026-274619","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:10:27Z","timestamp":1791216627000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2026-274619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":9,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10,5]]},"published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1136\/bcr-2026-274619"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2026-274619","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]}}}