{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:02:05Z","timestamp":1784901725719,"version":"3.55.0"},"reference-count":11,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,7,11]]},"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>Early neonatal hyperkalaemia is uncommon but may cause life-threatening arrhythmias if untreated. While most cases occur in extremely low-birth-weight infants after 24 hours of life, hyperkalaemia within the first few hours after birth is unusual.<\/jats:p>\n                  <jats:p>Magnesium sulfate, commonly used for pre-eclampsia, crosses the placenta and can cause neonatal hypermagnesaemia, which may disrupt potassium balance by inhibiting sodium\u2013potassium adenosine triphosphatase activity and renal outer medullary potassium channel-mediated distal tubular potassium secretion.<\/jats:p>\n                  <jats:p>A preterm infant born at 33+4 weeks\u2019 gestation developed severe hyperkalaemia, with serum potassium 7.65 mmol\/L and hypermagnesaemia within 2 hours of life. Electrocardiography, urine output, acid\u2013base status and renal ultrasonography were normal. Postpartum maternal evaluation showed hypermagnesaemia and hyperkalaemia, suggesting a possible maternal contribution. Following rapid recognition and treatment with salbutamol and insulin\u2013dextrose, serum potassium normalised and no arrhythmias occurred.<\/jats:p>\n                  <jats:p>This case shows that early-onset neonatal hyperkalaemia can occur in moderately preterm infants after maternal magnesium sulfate exposure, highlighting the importance of early detection and management.<\/jats:p>","DOI":"10.1136\/bcr-2026-274813","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:10:30Z","timestamp":1784898630000},"page":"e274813","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Early-onset non-oliguric hyperkalaemia in a moderate preterm infant following maternal magnesium sulfate therapy"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8028-2326","authenticated-orcid":false,"given":"Pasupathi Raj","family":"Balamurugan","sequence":"first","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roma","family":"Debbarma","sequence":"additional","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhosh","family":"Shimpiger","sequence":"additional","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil Kumar","family":"JS","sequence":"additional","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-1133","authenticated-orcid":false,"given":"Sushil Kumar","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Neonatology, AIIMS Jodhpur, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"2026072406101801000_19.7.e274813.1","doi-asserted-by":"crossref","DOI":"10.1186\/s12887-018-1048-4","article-title":"Early-onset neonatal hyperkalemia associated with maternal hypermagnesemia: a case report","volume":"18","author":"Tanaka","year":"2018","journal-title":"BMC Pediatr"},{"key":"2026072406101801000_19.7.e274813.2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.pedneo.2022.06.011","article-title":"Maternal magnesium sulfate administration increases early-onset hyperkalemia 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Southeast","volume":"48","author":"Wutthigate","year":"2017","journal-title":"Asian J Trop Med Public Health"},{"key":"2026072406101801000_19.7.e274813.11","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2026-274813","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:10:31Z","timestamp":1784898631000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2026-274813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":11,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7,24]]},"published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1136\/bcr-2026-274813"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2026-274813","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}