{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:03:00Z","timestamp":1789646580861,"version":"4.0.0"},"reference-count":6,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,9,2]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>Ataxia-telangiectasia (AT) is a rare autosomal recessive disorder associated with immunodeficiency and an increased risk of malignancy. We report a young child with AT and severe combined immunodeficiency who initially presented with left periorbital swelling and was treated for a presumed periorbital infection. She later presented with fever and was diagnosed with pneumonia, requiring admission. Despite antimicrobial therapy and surgical drainage, the swelling persisted and progressed rapidly.<\/jats:p>\n                  <jats:p>MRI of the brain and orbits demonstrated complicated sinusitis with a medial extraconal lesion, suggesting an infectious process. However, there was no sustained clinical response, and microbiological studies remained negative. Repeat MRI showed a persistent lesion with extension into adjacent structures. Histopathological examination confirmed non-Hodgkin B-cell lymphoma with a high proliferative index (Ki-67~80%).<\/jats:p>\n                  <jats:p>This case highlights the importance of early reassessment in immunocompromised patients with an atypical clinical course.<\/jats:p>","DOI":"10.1136\/bcr-2026-275016","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:25:17Z","timestamp":1789644317000},"page":"e275016","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Orbital lymphoma presenting as preseptal cellulitis in a child with ataxia-telangiectasia"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6615-0214","authenticated-orcid":false,"given":"Farah Kanaan","family":"AlNasser","sequence":"first","affiliation":[{"name":"Ophthalmology, Kuwait Ministry of Health, Sabah Al-Nasser, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malak","family":"AlRashidi","sequence":"additional","affiliation":[{"name":"Kuwait University Health Sciences Center, Safat, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amna","family":"AlRashidi","sequence":"additional","affiliation":[{"name":"Ophthalmology, Kuwait Ministry of Health, Sabah Al-Nasser, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"AbdelBadie","sequence":"additional","affiliation":[{"name":"Ophthalmology, Kuwait Ministry of Health, Sabah Al-Nasser, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"2026091704251201000_19.9.e275016.1","doi-asserted-by":"crossref","DOI":"10.1186\/s13023-016-0543-7","article-title":"Ataxia telangiectasia: a review","volume":"11","author":"Rothblum-Oviatt","year":"2016","journal-title":"Orphanet J Rare Dis"},{"key":"2026091704251201000_19.9.e275016.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2018.05.006"},{"key":"2026091704251201000_19.9.e275016.3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-1709"},{"key":"2026091704251201000_19.9.e275016.4","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1038\/s41433-022-02266-1","article-title":"Paediatric orbital lymphoma; a case series and review of the literature","volume":"37","author":"Keren","year":"2023","journal-title":"Eye"},{"key":"2026091704251201000_19.9.e275016.5","article-title":"Orbital lymphoma masquerading as orbital cellulitis","volume":"2021","author":"Chaurasiya","year":"2021","journal-title":"Case Rep Ophthalmol Med"},{"key":"2026091704251201000_19.9.e275016.6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajoc.2025.102288","article-title":"Burkitt\u2019s lymphoma presenting as acute dacryocystitis in a 14-year-Old male with ataxia telangiectasia: A case report and review of the literature","volume":"38","author":"Khannejad","year":"2025","journal-title":"Am J Ophthalmol Case Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2026-275016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:25:18Z","timestamp":1789644318000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2026-275016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":6,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,17]]},"published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1136\/bcr-2026-275016"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2026-275016","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]}}}