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During admission, she deteriorated with urinary retention, areflexia and type 2 respiratory failure requiring intubation and ventilation and was commenced on intravenous immunoglobulin (IVIG). Cerebrospinal fluid analysis later demonstrated albumin-cytologic dissociation and repeat nerve conduction studies confirmed an acute inflammatory demyelinating polyradiculoneuropathy consistent with Guillain-Barr\u00e9 syndrome (GBS). She improved following intensive care and IVIG, with partial recovery of limb strength and functional status and was discharged to a rehabilitation facility. This case illustrates a rare but important possible association between RSV vaccination and GBS; highlights the diagnostic challenges of early presentations with non-specific symptoms and inconclusive investigations; and emphasises the need for serial assessment and early escalation of care to optimise patient outcomes.<\/jats:p>","DOI":"10.1136\/bcr-2026-276086","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:43:14Z","timestamp":1790862194000},"page":"e276086","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Guillain-Barr\u00e9 syndrome temporally associated with respiratory syncytial virus vaccination"],"prefix":"10.1136","volume":"19","author":[{"given":"Saeed","family":"Hreiz","sequence":"first","affiliation":[{"name":"Broomfield Hospital, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5962-776X","authenticated-orcid":false,"given":"Mohamad","family":"Abu Zaher","sequence":"additional","affiliation":[{"name":"Renal, Broomfield Hospital, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varghese-Kurien","family":"Thyparambil","sequence":"additional","affiliation":[{"name":"Broomfield Hospital, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Bettany","sequence":"additional","affiliation":[{"name":"Broomfield Hospital, Chelmsford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"2026100106251767000_19.10.e276086.1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1218-z"},{"key":"2026100106251767000_19.10.e276086.2","unstructured":"UK Health Security Agency . 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