{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:27:44Z","timestamp":1790375264595,"version":"4.1.0"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Because body fluids and blood have a tendency to adhere to transesophageal echo devices, a high level of sterilisation is required when cleaning them. Ortho-phthalaldehyde (OPA) has been widely used in Japan since being approved as a high-level sterilant. The authors report a patient with widespread, severe skin and mucous membrane damage of the lip, tongue, pharynx and oesophagus areas that was attributed to inadequate washing after the sterilisation of a transesophageal echo device with OPA. This patient experienced sequelae, which did not improve after more than 1 year of continuous treatment. When using medical devices sterilised with OPA, the use of a probe cover, when applicable, is recommended and complete washing prior to use is required.<\/jats:p>","DOI":"10.1136\/bcr.02.2010.2709","type":"journal-article","created":{"date-parts":[[2011,2,2]],"date-time":"2011-02-02T14:49:56Z","timestamp":1296658196000},"page":"bcr0220102709","source":"Crossref","is-referenced-by-count":4,"title":["Ortho-phthalaldehyde-induced skin mucous membrane damage from inadequate washing: Figure 1"],"prefix":"10.1136","volume":"2011","author":[{"given":"Masaru","family":"Horikiri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susam","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komei","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2011,2,2]]},"reference":[{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.1","unstructured":"Spaulding EH . Disinfection, Sterilization and Preservation. First edition. Philadelphia, PA: Lea & Febiger 1968:517\u201331."},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.57.11.752"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.1999.00239.x"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.4","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2000.043003150.x"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.5","first-page":"82","article-title":"New high level disinfectant (Orthophthalaldehyde) for flexible endoscope application","volume":"3","author":"Oka","year":"2001","journal-title":"Kinosui Iryo Kenkyu"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1999.00791.x"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.7","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1213\/01.ANE.0000083641.58267.0C","article-title":"Chemical burn injury secondary to intraoperative transesophageal echocardiography","volume":"97","author":"Venticinque","year":"2003","journal-title":"Anesth Analg"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.8","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1177\/014556130808701013","article-title":"Oropharyngeal and laryngeal burn resulting from exposure to endoscope disinfectant: a case report","volume":"87","author":"Senchak","year":"2008","journal-title":"Ear Nose Throat J"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.9","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1097\/00000542-200310000-00049","article-title":"Perioral stains after ortho-phthalaldehyde disinfection of echo probes","volume":"99","author":"Streckenbach","year":"2003","journal-title":"Anesthesiology"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.04.031"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.11","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.C-06-51"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.12","first-page":"1705","article-title":"Bullous keratopathy after cataract surgery using orth phthalaldehyde for disinfection","volume":"59","author":"Kono","year":"2005","journal-title":"Jpn J Clin Ophthalmol"},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.13","unstructured":"Johnson and Johnson. Cidexplus 28 Day Solution. An instruction manual, 2005, 1\u20132."},{"key":"2025042701323621000_2011.jan29_1.bcr0220102709.14","unstructured":"Johnson and Johnson. DISOPA Solution 0.55%. An instruction manual, 2005, 1\u20132."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.02.2010.2709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:32:44Z","timestamp":1745742764000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.02.2010.2709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":14,"alternative-id":["10.1136\/bcr.02.2010.2709"],"URL":"https:\/\/doi.org\/10.1136\/bcr.02.2010.2709","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}