{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T15:30:15Z","timestamp":1764084615513,"version":"3.40.4"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>The authors report the case of a 4-year-old male child with a background of Down\u2019s syndrome (Trisomy 21) and a definitive repair of a balanced complete atrioventricular septal defect (CAVSD) at 3 months of age who experienced acute pulmonary oedema at high altitude (2000 m) while on holiday with his parents. The authors discuss and review the literature on the effect of altitude on children with Down\u2019s syndrome and postoperative CAVSD repair. The authors propose that further research is needed into this area in this specific group of patients, so advice can be given to families prior to flying or travelling.<\/jats:p>","DOI":"10.1136\/bcr.02.2011.3866","type":"journal-article","created":{"date-parts":[[2011,4,13]],"date-time":"2011-04-13T13:53:09Z","timestamp":1302702789000},"page":"bcr0220113866","source":"Crossref","is-referenced-by-count":3,"title":["Acute altitude induced hypoxia in a child with Down\u2019s syndrome following postoperative repair of complete atrioventricular septal defect"],"prefix":"10.1136","volume":"2011","author":[{"given":"Michael","family":"Griksaitis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Ang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,4,13]]},"reference":[{"doi-asserted-by":"publisher","key":"2025042707262946000_2011.apr12_1.bcr0220113866.1","DOI":"10.1016\/S0022-3476(75)80142-9"},{"doi-asserted-by":"publisher","key":"2025042707262946000_2011.apr12_1.bcr0220113866.2","DOI":"10.1136\/adc.2007.126672"},{"doi-asserted-by":"publisher","key":"2025042707262946000_2011.apr12_1.bcr0220113866.3","DOI":"10.1542\/peds.108.2.443"},{"doi-asserted-by":"publisher","key":"2025042707262946000_2011.apr12_1.bcr0220113866.4","DOI":"10.1016\/j.pcad.2010.02.004"},{"key":"2025042707262946000_2011.apr12_1.bcr0220113866.5","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1056\/NEJM198211043071902","article-title":"Pulmonary hypoplasia in Down\u00e2\u0080\u0099s syndrome.","volume":"307","author":"Cooney","year":"1982","journal-title":"N Engl J Med"},{"key":"2025042707262946000_2011.apr12_1.bcr0220113866.6","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/ppul.1950050405","article-title":"Diminished radial count is found only postnatally in Down\u00e2\u0080\u0099s syndrome.","volume":"5","author":"Cooney","year":"1988","journal-title":"Pediatr Pulmonol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.02.2011.3866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:26:40Z","timestamp":1745764000000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.02.2011.3866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":6,"alternative-id":["10.1136\/bcr.02.2011.3866"],"URL":"https:\/\/doi.org\/10.1136\/bcr.02.2011.3866","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2011]]}}}