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This was successfully carried out but 4 h later, he developed abdominal compartment syndrome and underwent a laparotomy and splenectomy. Subsequently, bone marrow aspirates were taken which showed granulocytic hyperplasia. Cytogenetic studies confirmed the presence of Philadelphia Chromosome and he was started on Imatinib. It is now 5 months since diagnosis and he has achieved complete haematological and cytogenetic response.<\/jats:p>","DOI":"10.1136\/bcr.02.2011.3879","type":"journal-article","created":{"date-parts":[[2011,3,24]],"date-time":"2011-03-24T11:08:08Z","timestamp":1300964888000},"page":"bcr0220113879","source":"Crossref","is-referenced-by-count":9,"title":["Spontaneous splenic rupture: an unusual presentation of CML"],"prefix":"10.1136","volume":"2011","author":[{"given":"Sadaf","family":"Jafferbhoy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Chantry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Atkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda","family":"Wyld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2011,3,24]]},"reference":[{"key":"2025082701382753000_2011.mar16_1.bcr0220113879.1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1742-1241.2003.tb10474.x","article-title":"Spontaneous rupture of a normal spleen.","volume":"57","author":"Paulvannan","year":"2003","journal-title":"Int J Clin Pract"},{"key":"2025082701382753000_2011.mar16_1.bcr0220113879.2","first-page":"739","article-title":". 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