{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T09:08:21Z","timestamp":1764493701701,"version":"3.40.4"},"reference-count":30,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Diffuse cutaneous mastocytosis (DCM) is a rare, severe, variant of cutaneous mastocytosis. The authors report the case of a male infant who developed maculae and maculopapulae on his legs and abdomen when aged 3.5 months, which spread to all body surfaces within weeks. Diagnosis of DCM was made at the age of 6 months when he had developed extensive bullous eruptions, generalised pruritus, flushing and abdominal pain. Treatment was started with oral dimethindine maleate. At the age of 18 months, oral sodium cromoglicate (SCG) was introduced. At the age of 23 months, additional treatment was started with a cutaneous emulsion containing 4% SCG. Continued treatment with oral dimethindine maleate, oral SCG with the dose maintained at 25 mg\/kg\/day, and SCG 4% cutaneous emulsion applied two to four times daily has resulted in a steady improvement of symptoms and skin appearance.<\/jats:p>","DOI":"10.1136\/bcr.02.2011.3910","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T11:10:40Z","timestamp":1309432240000},"page":"bcr0220113910","source":"Crossref","is-referenced-by-count":14,"title":["Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant"],"prefix":"10.1136","volume":"2011","author":[{"given":"Alan Martin","family":"Edwards","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0160t\u011bp\u00e1nka","family":"\u010capkov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,6,30]]},"reference":[{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(01)00038-8"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-002-0575-z"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2008.00738.x"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.4","first-page":"115","article-title":"Disodium cromoglycate (Intal)","volume":"5","author":"Cox","year":"1970","journal-title":"Adv Drug Res"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.5","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198900371-00009"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1992.tb03102.x"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.7","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/icb.1995.37","article-title":"Ultraviolet B irradiation of skin induces mast cell degranulation and release of tumour necrosis factor-alpha.","volume":"73","author":"Walsh","year":"1995","journal-title":"Immunol Cell Biol"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.8","doi-asserted-by":"publisher","DOI":"10.1159\/000314164"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1980.tb10898.x"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.10","doi-asserted-by":"publisher","DOI":"10.1042\/cs0680227"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09516.x"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.12","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp628"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.13","first-page":"684","article-title":"Systemic mastocytosis: control of lifelong diarrhea by ingested disodium cromoglycate.","volume":"111","author":"Dolovich","year":"1974","journal-title":"Can Med Assoc J"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197908303010903"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb00800.x"},{"key":"2025042707431850000_2011.jun23_1.bcr0220113910.16","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0002-9343(85)90454-1","article-title":"Comparison of the therapeutic efficacy of cromolyn sodium with that of combined chlorpheniramine and cimetidine in systemic mastocytosis. 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