{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:03:08Z","timestamp":1790521388602,"version":"4.1.0"},"reference-count":20,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:title\/>\n               <jats:p>Renal cell carcinoma is known to have blood-borne metastasis. This is usually to the bone, lungs and brain. Other unusual metastatic presentations such as skin and bowel metastasis have also been described. In most cases, the metastasis occurs as a late manifestation in a patient with known primary renal cell carcinoma. A rare synchronous presentation of skin and duodenal metastasis in an otherwise asymptomatic patient is reported here. This patient presented with a skin lesion that, on excision, brought up the diagnosis of metastatic renal cell carcinoma. While the patient was waiting for surgery, she also developed melena that, on gastroscopy, confirmed a duodenal metastasis. This case highlights the importance of early recognition of otherwise unrelated lesions as presentations for an advanced renal malignancy.<\/jats:p>","DOI":"10.1136\/bcr.02.2012.5764","type":"journal-article","created":{"date-parts":[[2012,6,8]],"date-time":"2012-06-08T07:28:09Z","timestamp":1339140489000},"page":"bcr0220125764","source":"Crossref","is-referenced-by-count":8,"title":["Asymptomatic renal cell carcinoma with metastasis to the skin and duodenum: a case report and review of the literature"],"prefix":"10.1136","volume":"2012","author":[{"given":"Adhip","family":"Mandal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Littler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabor","family":"Libertiny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,6,8]]},"reference":[{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.1","unstructured":"McDougal WS Wein AJ Kavoussi LR . 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Primary Neoplasms of the kidney. In: Brady HR Wilcox CS , eds. Therapy in nephrology and hypertension: a companion to Brenner and Rector's\u2014The Kidney. Philadelphia: WB Saunders, 1998:337\u201340."},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.10","first-page":"1","article-title":"Current management of advanced and metastatic renal cell carcinoma","volume":"7","author":"Ather","year":"2010","journal-title":"Urol J"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.01.014"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.12","first-page":"913734","article-title":"Renal cell carcinoma presenting with cutaneous metastasis: a case report","volume":"2010","author":"Kandemir","year":"2010","journal-title":"Case Report Med"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.13","first-page":"1939","article-title":"Renal cell carcinoma metastatic to skin","volume":"20","author":"Koga","year":"2000","journal-title":"Anticancer Res"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.14","first-page":"287","article-title":"Cutaneous metastasis from silent renal cell carcinoma","volume":"50","author":"Preetha","year":"2004","journal-title":"J Postgrad Med"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.15","first-page":"2001","article-title":"Duodenal metastasis: an uncommon cause of occult small intestinal bleeding","volume":"62","author":"Loualidi","year":"2004","journal-title":"Neth J Med"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.16","doi-asserted-by":"crossref","first-page":"3968","DOI":"10.1111\/j.1440-1673.1995.tb00320.x","article-title":"Duodenal haemorrhage resulting from renal cell carcinoma metastasis","volume":"39","author":"Black","year":"1995","journal-title":"Australas Radiol"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.17","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v3.i6.99"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.18","doi-asserted-by":"publisher","DOI":"10.1159\/000327996"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.19","doi-asserted-by":"publisher","DOI":"10.1157\/13097378"},{"key":"2025082704001186000_2012.jun07_1.bcr0220125764.20","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2010.57"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.02.2012.5764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:00:25Z","timestamp":1756292425000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.02.2012.5764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,8]]},"references-count":20,"alternative-id":["10.1136\/bcr.02.2012.5764"],"URL":"https:\/\/doi.org\/10.1136\/bcr.02.2012.5764","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,8]]}}}