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MRI of the brain revealed frontal lobe and cerebellar atrophy, while neuropsychological assessment identified deficit in memory processing and executive functions. Despite appropriate correction of primary hypothyroidism with levothyroxine, the patient remained delusional with respect to age and employment although he showed some improvement in memory. Capacity for self-care remained poor; thus, he was eventually transferred to sheltered housing with rehabilitation.<\/jats:p>","DOI":"10.1136\/bcr.03.2010.2841","type":"journal-article","created":{"date-parts":[[2010,9,17]],"date-time":"2010-09-17T06:43:02Z","timestamp":1284705782000},"page":"bcr0320102841","source":"Crossref","is-referenced-by-count":13,"title":["Myxoedema madness"],"prefix":"10.1136","volume":"2010","author":[{"given":"Laura","family":"Azzopardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Murfin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Sharda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanda","family":"De Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,9,17]]},"reference":[{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.1","first-page":"1","article-title":"Report of the Committee of the Clinical Society of London nominated December 1, 1883, to investigate the subject of myxoedema","volume":"21","year":"1888","journal-title":"Trans Clin Soc Lond"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0033-3182(83)73255-X","article-title":"Psychiatric effects of thyroid hormone disturbance","volume":"24","author":"Hall","year":"1983","journal-title":"Psychosomatics"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4627.555"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.4","first-page":"260","article-title":"Hypothyroidism and psychosis: a case illustration of the diagnostic dilemma in psychiatry","volume":"39","author":"Granet","year":"1978","journal-title":"J Clin Psychiatry"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.5","doi-asserted-by":"publisher","DOI":"10.2190\/EGKP-GK8D-HA3T-76C2"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.6","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-196306000-00008"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-8343(02)00190-1"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.3.686"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.9","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.8.3864"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.10","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199909000-00005"},{"key":"2025082702421534000_2010.sep16_1.bcr0320102841.11","first-page":"1101","article-title":"Electroencephalographic changes in hypothyroidism","volume":"60","author":"Gupta","year":"1972","journal-title":"Indian J Med Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.03.2010.2841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:42:25Z","timestamp":1756287745000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.03.2010.2841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":11,"alternative-id":["10.1136\/bcr.03.2010.2841"],"URL":"https:\/\/doi.org\/10.1136\/bcr.03.2010.2841","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}