{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:12:58Z","timestamp":1782738778753,"version":"3.54.5"},"reference-count":17,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>Type 1 diabetes mellitus in children has been associated with other autoimmune diseases, especially coeliac disease and autoimmune thyroiditis. This association may be the result of a common pathogenic background. We describe the case of a girl with type 1 diabetes mellitus who developed icterus due to autoimmune hepatitis, a disease rarely found in children. Thyroiditis-associated and diabetes-associated autoantibodies were also present. Human leucocyte antigen typing revealed DRB1*03 heterozygosity, which has been associated with the occurrence of both autoimmune hepatitis and type 1 diabetes. This finding implies that similar pathogenic pathways may be involved in different autoimmune diseases including type 1 diabetes and autoimmune hepatitis. The patient was successfully treated with prednisolone and azathioprine. Autoimmune hepatitis can be a serious co-occurring disease in patients with type 1 diabetes.<\/jats:p>","DOI":"10.1136\/bcr.04.2010.2899","type":"journal-article","created":{"date-parts":[[2010,11,26]],"date-time":"2010-11-26T10:19:08Z","timestamp":1290766748000},"page":"bcr0420102899","source":"Crossref","is-referenced-by-count":4,"title":["A girl with type 1 diabetes and a yellowish appearance: Figure 1"],"prefix":"10.1136","volume":"2010","author":[{"given":"I C L Kremer","family":"Hovinga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E D","family":"Stam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M L","family":"Mearin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Mul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2010,11,26]]},"reference":[{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60568-7"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.2","doi-asserted-by":"publisher","DOI":"10.1159\/000201108"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)00805-5"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.4","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025100328425"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(99)80297-9"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.6","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.3360"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.7","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250308"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.8","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181a1c265"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.9","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.4.589"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.10","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3282fa1400"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1365-2036.2010.04241.x","article-title":"Review article: the modern management of autoimmune hepatitis","volume":"31","author":"Yeoman","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.12","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/hep.23584","article-title":"Diagnosis and management of autoimmune hepatitis","volume":"51","author":"Manns","year":"2010","journal-title":"Hepatology"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.13","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/MCG.0b013e31802dbdfc","article-title":"Frequency of concurrent autoimmune disorders in patients with autoimmune hepatitis: effect of age, gender, and genetic background","volume":"42","author":"Bittencourt","year":"2008","journal-title":"J Clin Gastroenterol"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.14","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1515\/JPEM.2002.15.6.831","article-title":"Diabetes mellitus-related autoantibodies in childhood autoimmune hepatitis","volume":"15","author":"da Silva","year":"2002","journal-title":"J Pediatr Endocrinol Metab"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05415-0"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.16","first-page":"268","article-title":"Prediction of type 1 diabetes: the natural history of the prediabetic period","volume":"552","author":"Eisenbarth","year":"2004","journal-title":"Adv Exp Med Biol"},{"key":"2025082803495290000_2010.nov24_1.bcr0420102899.17","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-35705"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.04.2010.2899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:49:57Z","timestamp":1756378197000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.04.2010.2899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":17,"alternative-id":["10.1136\/bcr.04.2010.2899"],"URL":"https:\/\/doi.org\/10.1136\/bcr.04.2010.2899","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}