{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T14:03:06Z","timestamp":1769608986769,"version":"3.49.0"},"reference-count":4,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>In this article the authors present a case of pathological neonatal jaundice resistant to phototherapy in a baby with a family history of Gilbert\u2019s syndrome and hereditary spherocytosis. Her presentation was ultimately explained with a diagnosis of both conditions, and required treatment with phenobarbitone. The authors discuss the mechanism by which Gilbert\u2019s syndrome results in hyperbilirubinaemia and its similarities with Crigler\u2013Najjar syndrome. The presentation of hereditary spherocystosis in the neonatal period is also explored, as is the mechanism of exaggerated hyperbilirubinaemia when the two conditions co-exist.<\/jats:p>","DOI":"10.1136\/bcr.05.2011.4293","type":"journal-article","created":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T15:13:53Z","timestamp":1311952433000},"page":"bcr0520114293","source":"Crossref","is-referenced-by-count":3,"title":["Intractable neonatal jaundice due to hereditary spherocytosis and Gilbert\u2019s syndrome"],"prefix":"10.1136","volume":"2011","author":[{"given":"Abdul Qader Tahir","family":"Ismail","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjum","family":"Gandhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagui","family":"El-Shimy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,7,29]]},"reference":[{"key":"2025042707541128000_2011.jul28_1.bcr0520114293.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199511023331802"},{"key":"2025042707541128000_2011.jul28_1.bcr0520114293.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)91273-8"},{"key":"2025042707541128000_2011.jul28_1.bcr0520114293.3","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1182\/blood.V94.7.2259.419k42_2259_2262","article-title":"Coinheritance of Gilbert syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis.","volume":"94","author":"del Giudice","year":"1999","journal-title":"Blood"},{"key":"2025042707541128000_2011.jul28_1.bcr0520114293.4","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1182\/blood.V91.3.1093","article-title":"UGT1 promoter polymorphism accounts for increased neonatal appearance of hereditary spherocytosis.","volume":"91","author":"Iolascon","year":"1998","journal-title":"Blood"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.05.2011.4293","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:54:20Z","timestamp":1745765660000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.05.2011.4293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,29]]},"references-count":4,"alternative-id":["10.1136\/bcr.05.2011.4293"],"URL":"https:\/\/doi.org\/10.1136\/bcr.05.2011.4293","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,29]]}}}