{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:40:01Z","timestamp":1756377601598,"version":"3.44.0"},"reference-count":4,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"abstract":"<jats:p>Wegener\u2019s granulomatosis (WG) is a multisystemic necrotising granulomatous vasculitis of small and medium sized vessels, that primarily involves the upper and lower respiratory tracts, lung tissues and kidneys. Serum antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker of WG. Whereas the peripheral nervous system is often involved in WG, central nervous system manifestations are reported only in 2\u20138%, and are rarely present at onset. We report on a patient with atypical neurological presentation of ANCA negative WG in whom the diagnosis was made only after a meningeal biopsy.<\/jats:p>","DOI":"10.1136\/bcr.06.2008.0283","type":"journal-article","created":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T13:17:58Z","timestamp":1227273478000},"page":"bcr0620080283","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Wegener\u2019s granulomatosis confined to nervous system"],"prefix":"10.1136","volume":"2008","author":[{"given":"M","family":"Lucchetta","sequence":"first","affiliation":[{"name":"University of Padova, Neurosciences, Via Giustiniani 5, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Favero","sequence":"additional","affiliation":[{"name":"University of Padova, Rheumatology, Via Giustiniani 2, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Schiavon","sequence":"additional","affiliation":[{"name":"University of Padova, Rheumatology, Via Giustiniani 2, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Cagnin","sequence":"additional","affiliation":[{"name":"University of Padova, Neurosciences, Via Giustiniani 5, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Manara","sequence":"additional","affiliation":[{"name":"University of Padova, Neuroradiology, Via Giustiniani 5, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Rotilio","sequence":"additional","affiliation":[{"name":"University of Padova, Neurosciences, Via Giustiniani 5, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Orvieto","sequence":"additional","affiliation":[{"name":"University of Padova, Pathology, Via Gabelli, Padova, Italy, 35100"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Giannini","sequence":"additional","affiliation":[{"name":"Mayo Clinic College of Medicine, Laboratory Medicine and Pathology, Rochester Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Briani","sequence":"additional","affiliation":[{"name":"University of Padova, Neurosciences, Via Giustiniani 5, Padova, Italy, 35128"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"2025082803210133000_2008.aug05_1.bcr0620080283.1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-6-488"},{"key":"2025082803210133000_2008.aug05_1.bcr0620080283.2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410330103"},{"key":"2025082803210133000_2008.aug05_1.bcr0620080283.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.05.029"},{"key":"2025082803210133000_2008.aug05_1.bcr0620080283.4","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780360312"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.06.2008.0283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:21:09Z","timestamp":1756376469000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.06.2008.0283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":4,"alternative-id":["10.1136\/bcr.06.2008.0283"],"URL":"https:\/\/doi.org\/10.1136\/bcr.06.2008.0283","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}