{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T15:49:12Z","timestamp":1779205752607,"version":"3.51.4"},"reference-count":2,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>An elderly gentleman presented to hospital with recurrent blackout episodes consistent with syncope and a 3-month history of right ear pain. Significant postural hypotension was recorded. White cell count and C reactive protein were elevated. MRI of the head and neck revealed a soft tissue abnormality in the right nasopharynx and base of skull. Tissue biopsies were obtained and microbiology specimens revealed a mixed growth of pseudomonas and diphtheroids. There was no histological evidence of malignancy.<\/jats:p>\n               <jats:p>A diagnosis of skull base infection was made. Infective involvement of the carotid sinus was considered to be the cause of the recurrent syncope and postural hypotension.<\/jats:p>\n               <jats:p>The patient responded well to a 12-week course of intravenous meropenem. Inflammatory markers returned to normal and a repeat MRI after 3 months of treatment showed significant resolution of infection. The syncopal episodes and orthostatic hypotension resolved in parallel with treatment of infection.<\/jats:p>","DOI":"10.1136\/bcr.06.2010.3109","type":"journal-article","created":{"date-parts":[[2010,11,2]],"date-time":"2010-11-02T08:03:10Z","timestamp":1288684990000},"page":"bcr0620103109","source":"Crossref","is-referenced-by-count":2,"title":["Recurrent syncope and chronic ear pain"],"prefix":"10.1136","volume":"2010","author":[{"given":"Andrew","family":"Clegg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Daverede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winson","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Loney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,11,2]]},"reference":[{"key":"2025082707492901000_2010.oct29_1.bcr0620103109.1","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200310000-00002"},{"key":"2025082707492901000_2010.oct29_1.bcr0620103109.2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.3033"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.06.2010.3109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:49:40Z","timestamp":1756306180000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.06.2010.3109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":2,"alternative-id":["10.1136\/bcr.06.2010.3109"],"URL":"https:\/\/doi.org\/10.1136\/bcr.06.2010.3109","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}