{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T04:07:47Z","timestamp":1745640467412,"version":"3.40.4"},"reference-count":21,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Described is a case of triphasic thyroid response in a 53-year-old man while undergoing combination interferon \u03b1-2b and ribavirin treatment for chronic hepatitis C infection. He developed the classical biphasic thyroiditis during treatment and was treated expectantly. However, 8 weeks after the completion of therapy, he developed T3-Graves-like thyrotoxicosis, which was confirmed with a diffuse-uptake thyroid scan and positive thyroid stimulating immunoglobulin. He was treated as having Graves\u2019 disease arising de novo with thiourea, and he achieved rapid remission. This is thought to be only the second case described, and it offers a unique opportunity to understand the possible pathogenesis of this fascinating condition. This is a relative novel entity and highlights the need for continuing thyroid monitor after treatment. Management also needs to be specific for each particular phase of the condition.<\/jats:p>","DOI":"10.1136\/bcr.07.2008.0464","type":"journal-article","created":{"date-parts":[[2009,9,15]],"date-time":"2009-09-15T10:18:50Z","timestamp":1253009930000},"page":"bcr0720080464","source":"Crossref","is-referenced-by-count":1,"title":["The swinging thyroid in hepatitis C infection and interferon therapy"],"prefix":"10.1136","volume":"2009","author":[{"given":"Huy A","family":"Tran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2009,9,15]]},"reference":[{"key":"2025042508154472000_2009.sep15_1.bcr0720080464.1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2523562"},{"key":"2025042508154472000_2009.sep15_1.bcr0720080464.2","unstructured":"World Health Organization. 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On behalf of the Royal College of Physicians of London and the British Society of Gastroentrology. Clinical Guidelines on the management of hepatitis C. http:\/\/www.bsg.org.uk\/pdf_word_docs\/clinguidehepc.pdf (accessed 15 July 2008)."},{"key":"2025042508154472000_2009.sep15_1.bcr0720080464.19","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.011"},{"key":"2025042508154472000_2009.sep15_1.bcr0720080464.20","unstructured":"National Institutes of Health. Management of hepatitis C: 2002 National Institutes of Health Consensus Conference Statement 2002; 19: 1\u201346."},{"key":"2025042508154472000_2009.sep15_1.bcr0720080464.21","unstructured":"The National Academy of Clinical Biochemistry. 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