{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T04:07:32Z","timestamp":1745640452144,"version":"3.40.4"},"reference-count":26,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>In newborn infants, acute perinatal hypoxic\/ischaemic events and associated hyperoxia\/reperfusion injury frequently lead to devastating neonatal brain damage. The present report concerns a 3-week-old boy from Pakistan with d-transposition of the great arteries (d-TGA), prolonged and severe hypoxaemia, and multiresistant bacterial sepsis. The term newborn infant underwent public airline transportation to Europe and presented on the airport\u2019s runway with severe hypoxaemia (pulsoximetric oxygen saturations (SpO2) 17%) and systemic hypotension. The patient eventually underwent late balloon atrial septostomy, followed by a successful two-stage arterial switch operation. A clinical follow-up 3\u20135 years later revealed lack of cerebral dysfunction, adequate neurodevelopment, good biventricular function, regular coronary flow, as well as normal ECG, blood pressure and SpO<jats:sub>2<\/jats:sub>. The findings may indicate the neonatal brain adjusts better to chronic, slowly worsening hypoxia than to acute hypoxia (eg, \u201cbirth asphyxia\u201d), and also suggests a greater tolerance for chronic hypoxia in neonates vs adults.<\/jats:p>","DOI":"10.1136\/bcr.07.2008.0500","type":"journal-article","created":{"date-parts":[[2009,3,17]],"date-time":"2009-03-17T19:41:52Z","timestamp":1237318912000},"page":"bcr0720080500","source":"Crossref","is-referenced-by-count":0,"title":["Arrival and survival of a 3-week-old boy from Pakistan with an arterial oxygen saturation of 17%"],"prefix":"10.1136","volume":"2009","author":[{"given":"Georg","family":"Hansmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Haas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masood","family":"Sadiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Brook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Peter","family":"Gildein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2009,3,17]]},"reference":[{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)64181-1"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.28-4-123"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.3","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000144141.18560.CF"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.9.1209"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.5","first-page":"8","article-title":"Balloon atrial septostomy: history and technique","volume":"26","author":"Boehm","year":"2006","journal-title":"Images Paediatr Cardiol"},{"issue":"Suppl 3","key":"2025042507362953000_2009.mar08_1.bcr0720080500.6","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1017\/S1047951106001041","article-title":"Is the arterial switch operation as good over the long term as we thought it would be?","volume":"16","author":"Cohen","year":"2006","journal-title":"Cardiol Young"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.566752"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.8","unstructured":"Bellman M Lingnam S Aukett A . Manual for schedule of growing skills II (SGS-II). London, UK: The NFER-NELSON Publishing Company Ltd, 1996."},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.9","doi-asserted-by":"publisher","DOI":"10.1159\/000047103"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.10","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.91"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.11","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200412-1740OC"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17203-6"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041996"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.14","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2839"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcps050929"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.16","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3310"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2008.04.027"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.18","unstructured":"Park MK . Pediatric cardiology for practitioners, 5th edn. St Louis, Missouri, USA: Mosby, 2008."},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(03)00071-7"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.20","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(93)90364-Q"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.21","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1161\/01.STR.30.9.1851","article-title":"Attenuated stroke severity after prodromal TIA: a role for ischemic tolerance in the brain?","volume":"30","author":"Weih","year":"1999","journal-title":"Stroke"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14412-1"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2006.12.020"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.24","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067393"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.25","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.594804"},{"key":"2025042507362953000_2009.mar08_1.bcr0720080500.26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe078138"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.07.2008.0500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T14:36:39Z","timestamp":1745591799000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.07.2008.0500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":26,"alternative-id":["10.1136\/bcr.07.2008.0500"],"URL":"https:\/\/doi.org\/10.1136\/bcr.07.2008.0500","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2009]]}}}