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One particular lesion in the breast was slow to heal and was monitored with ultrasound imaging. Subsequent cross-sectional imaging revealed that this was, in fact, a large mediastinal abscess, eroding the manubrium and lying within close proximity of the aorta. The patient was eventually referred to a cardiothoracic unit for complete evacuation of this lesion. Following a prolonged illness and treatment period, the patient recovered well and successfully resumed employment.<\/jats:p>","DOI":"10.1136\/bcr.07.2009.2082","type":"journal-article","created":{"date-parts":[[2010,8,19]],"date-time":"2010-08-19T12:19:53Z","timestamp":1282220393000},"page":"bcr0720092082","source":"Crossref","is-referenced-by-count":1,"title":["A case of severe staphylococcal septicaemia: septic arthritis and a mediastinal abscess following leflunamide therapy for rheumatoid arthritis"],"prefix":"10.1136","volume":"2010","author":[{"given":"Anjali","family":"Balasanthiran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tannaz","family":"Vakilgilani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Darzy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Axon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,8,19]]},"reference":[{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2007.06.002"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2007.05.003"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.3","first-page":"387","article-title":"The risk of hospitalized infection in patients with rheumatoid arthritis","volume":"35","author":"Smitten","year":"2008","journal-title":"J Rheumatol"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.4","first-page":"2201","article-title":"Leflunomide-associated infections in rheumatoid arthritis","volume":"34","author":"Jenks","year":"2007","journal-title":"J Rheumatol"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.5","first-page":"369","article-title":"Multiple tendon rupture at unusual sites in rheumatoid arthritis","volume":"14","author":"Lauzon","year":"1987","journal-title":"J Rheumatol"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.6","first-page":"36","article-title":"Tendon ruptures in rheumatic patients","volume":"66","author":"Wanivenhaus","year":"2007","journal-title":"Z Rheumatol"},{"key":"2025082800405576000_2010.aug17_1.bcr0720092082.7","first-page":"235","article-title":"Rupture of the Achilles tendon in rheumatoid arthritis with histological evidence of ethesitis. 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