{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:10:00Z","timestamp":1756307400902,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"abstract":"<jats:p>Intravenous glucose administration is the most common cause of hypophosphataemia in hospitalised patients. While most of these cases are asymptomatic, severe hypophosphataemia, when combined with phosphorus depletion, can cause acute neuropathy that mimics Guillain\u2013Barr\u00e9 syndrome. A malnourished patient who received intravenous hyperalimentation (IVH) without intravenous phosphate (IP) developed hypophosphataemia and acute sensorimotor neuropathy. F waves in the peripheral nerve trunk were absent or diminished, while nerve conduction velocities were nearly normal. The sural nerve biopsy revealed the presence of some subperineurial oedema and mild axonal atrophy. Prompt IP administration reversed the patients\u2019 neurological symptoms and normalised F waves. Our data suggest that hypophosphataemia plays a role in the pathogenesis of neuropathy that develops in patients following IVH without IP.<\/jats:p>","DOI":"10.1136\/bcr.08.2008.0718","type":"journal-article","created":{"date-parts":[[2009,2,2]],"date-time":"2009-02-02T06:49:47Z","timestamp":1233557387000},"page":"bcr0820080718","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Hypophosphataemic neuropathy during total parenteral nutrition"],"prefix":"10.1136","volume":"2009","author":[{"given":"Yohei","family":"Iguchi","sequence":"first","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Neurology, 65, Tsurumai-cho, showa-ku, Nagoya, 466-8550, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Mori","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Neurology, 65, Tsurumai-cho, showa-ku, Nagoya, 466-8550, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruki","family":"Koike","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Neurology, 65, Tsurumai-cho, showa-ku, Nagoya, 466-8550, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Mano","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nagoya First Hospital, Neurology, 3-35 Michishitacho, Nakamuraku, Nagoya, Aichi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoji","family":"Goto","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nagoya First Hospital, Neurology, 3-35 Michishitacho, Nakamuraku, Nagoya, Aichi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kato","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nagoya First Hospital, Neurology, 3-35 Michishitacho, Nakamuraku, Nagoya, Aichi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonobu","family":"Nakano","sequence":"additional","affiliation":[{"name":"Aichi Medical University, Stroke Center, Aichi 480-1195, Nagakute, Aichi, 480-1195, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Sobue","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Neurology, 65, Tsurumai-cho, showa-ku, Nagoya, 466-8550, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,8,9]]},"reference":[{"key":"2025082707291069000_2009.aug09_1.bcr0820080718.1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380010155016"},{"key":"2025082707291069000_2009.aug09_1.bcr0820080718.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197705122961908"},{"key":"2025082707291069000_2009.aug09_1.bcr0820080718.3","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1097\/00007611-198511000-00034","article-title":"Peripheral neuropathy with hypophosphatemia in a patient receiving intravenous hyperalimentation","volume":"78","author":"Yagnik","year":"1985","journal-title":"South Med J"},{"key":"2025082707291069000_2009.aug09_1.bcr0820080718.4","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199805)21:5<650::AID-MUS14>3.0.CO;2-Z"},{"key":"2025082707291069000_2009.aug09_1.bcr0820080718.5","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-74-4-562"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.08.2008.0718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:29:19Z","timestamp":1756304959000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.08.2008.0718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,9]]},"references-count":5,"alternative-id":["10.1136\/bcr.08.2008.0718"],"URL":"https:\/\/doi.org\/10.1136\/bcr.08.2008.0718","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,8,9]]}}}