{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:18:27Z","timestamp":1787066307078,"version":"build-2736575974"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>Churg\u2013Strauss syndrome (CSS) is a systemic vasculitis with frequent respiratory tract involvement. It can also affect the nervous system, notably the optic tract. The present work reports the case of a 65-year-old man diagnosed as having CSS in the context of several acute onset neurological symptoms including muscle weakness and signs of temporal arteritis, including bilateral anterior ischaemic optic neuropathy (ON). Electroretinograms (ERGs) and visual evoked potentials (VEPs) were performed. Flash ERGs were normal whereas VEPs were highly abnormal, showing a dramatic voltage reduction, thus confirming the ON. The vision outcome was poor. Ophthalmological presentations of CSS have rarely been reported, but no previous case of sudden blindness documented by combined ERG and VEP investigations were found in the literature. The present case strongly suggests that the occurrence of visual loss in the context of systemic inflammation with hypereosinophilia should lead to considering the diagnosis of CSS.<\/jats:p>","DOI":"10.1136\/bcr.08.2009.2219","type":"journal-article","created":{"date-parts":[[2010,10,12]],"date-time":"2010-10-12T08:53:01Z","timestamp":1286873581000},"page":"bcr0820092219","source":"Crossref","is-referenced-by-count":3,"title":["Initial neuro-ophthalmological manifestations in Churg\u2013Strauss syndrome"],"prefix":"10.1136","volume":"2010","author":[{"given":"Anne-Evelyne","family":"Vallet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Didelot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fitsum","family":"Guebre-Egziabher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Maugui\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2010,10,12]]},"reference":[{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.1","first-page":"277","article-title":"Allergic granulomatosis, allergic angiitis, and periarteritis nodosa","volume":"27","author":"Churg","year":"1951","journal-title":"Am J Pathol"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12518-4"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00557-7"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.4","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.039859"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00190718"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1983.01040020219011"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.77.2.118"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.8","first-page":"363","article-title":"Reversible monocular blindness complicating Churg-Strauss syndrome","volume":"21","author":"Alberts","year":"1994","journal-title":"J Rheumatol"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.9","first-page":"273","article-title":"Ischemic optic neuritis in Churg-Strauss syndrome","volume":"88","author":"Giorgi","year":"1997","journal-title":"Recenti Prog Med"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.10","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1212\/WNL.44.11.2200","article-title":"Anterior ischemic optic neuropathy in Churg-Strauss syndrome","volume":"44","author":"Kattah","year":"1994","journal-title":"Neurology"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.11","first-page":"505","article-title":"Churg-Strauss syndrome presenting as polymyositis","volume":"13","author":"De Vlam","year":"1995","journal-title":"Clin Exp Rheumatol"},{"key":"2025082722471110000_2010.oct11_1.bcr0820092219.12","first-page":"612","article-title":"Case of anterior ischemic optic neuropathy accompanied by Churg-Strauss syndrome (article in Japanese)","volume":"108","author":"Hayakawa","year":"2004","journal-title":"Nippon Ganka Gakkai Zasshi"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.08.2009.2219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:47:17Z","timestamp":1756360037000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.08.2009.2219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":12,"alternative-id":["10.1136\/bcr.08.2009.2219"],"URL":"https:\/\/doi.org\/10.1136\/bcr.08.2009.2219","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}