{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T06:00:42Z","timestamp":1776405642966,"version":"3.51.2"},"reference-count":3,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>A 16-year-old Bangladeshi girl presented with a 9-day history of an extensive pruritic, erythematous, papulovesicular skin eruption to both forearms. Appearance was 5 days following application of a home-made henna preparation. Examination revealed ulceration and scabbing along the whole henna pattern and early keloid formation. A diagnosis of type IV delayed hypersensitivity reaction superimposed by infection was initially made. As in this case, home-made henna preparations commonly combine commercial henna with black hair dye, paraphenylenediamine (PPD). PPD, widely known as \u2018black henna\u2019, darkens the pigment and precipitates the drying process. PPD is a potent contact allergen associated with a high incidence of hypersensitivity reactions. Despite treatment the patient was left with extensive keloid scarring in the pattern of the henna tattoo.<\/jats:p>","DOI":"10.1136\/bcr.09.2009.2277","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T09:08:15Z","timestamp":1286442495000},"page":"bcr0920092277","source":"Crossref","is-referenced-by-count":4,"title":["Severe type IV hypersensitivity to \u2018black henna\u2019 tattoo"],"prefix":"10.1136","volume":"2010","author":[{"given":"Vasileios","family":"Vasilakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernice","family":"Knight","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satnam","family":"Lidder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Frankton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,10,7]]},"reference":[{"key":"2025082703423473000_2010.oct06_1.bcr0920092277.1","first-page":"36","article-title":"Type IV hypersensitivity reaction to a temporary tattoo","volume":"20","author":"Sonnen","year":"2007","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"2025082703423473000_2010.oct06_1.bcr0920092277.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07275.x"},{"key":"2025082703423473000_2010.oct06_1.bcr0920092277.3","first-page":"253","article-title":"Management of keloids and hypertrophic scars","volume":"80","author":"Juckett","year":"2009","journal-title":"Am Fam Physician"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.09.2009.2277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:42:42Z","timestamp":1756291362000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.09.2009.2277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":3,"alternative-id":["10.1136\/bcr.09.2009.2277"],"URL":"https:\/\/doi.org\/10.1136\/bcr.09.2009.2277","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}