{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:10:01Z","timestamp":1756361401761,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>Buccal midazolam is a rescue medication to reduce the duration of or stop an epileptic seizure, and is used to prevent status epilepticus. It is available in various forms, including a buccal preparation with a strength of 10 mg\/1 ml. Midazolam is a licensed medication, but the buccal formulation is currently used off-licence. The prescriber takes ultimate responsibility for its use in this way. Administered by a trained person, it is receiving widespread acceptance as an alternative and effective treatment to rectally-administered diazepam in the community. The commonest side effects of midazolam are drowsiness and somnolence, although respiratory depression and paradoxical reactions, for example, agitation, restlessness and disorientation, may also occur. Hypotension is said to be a rare side effect, but with no reported cases in people administered buccal midazolam. The authors report a case of significant hypotension associated with administration of buccal midazolam for seizure management.<\/jats:p>","DOI":"10.1136\/bcr.09.2010.3371","type":"journal-article","created":{"date-parts":[[2010,12,16]],"date-time":"2010-12-16T12:09:51Z","timestamp":1292501391000},"page":"bcr0920103371","source":"Crossref","is-referenced-by-count":1,"title":["Significant hypotension following buccal midazolam administration"],"prefix":"10.1136","volume":"2010","author":[{"given":"Maria","family":"Kensche","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josemir W","family":"Sander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay M","family":"Sisodiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,12,16]]},"reference":[{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.1","unstructured":"British Medical Association, Royal Pharmaceutical Society of Great Britain: British National Formulary 59. British medical journal publishing group and pharmaceutical press, March 2010. http:\/\/bnf.org\/bnf\/bnf\/current\/6601.htm (accessed 21 September 2010)."},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2002.019836"},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.331.7518.673"},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.4","doi-asserted-by":"publisher","DOI":"10.1016\/0920-1211(91)90011-4"},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66909-7"},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.6","unstructured":"Penn Pharmaceutical Services. http:\/\/www.pennpharm.co.uk (accessed 21 September 2010)."},{"key":"2025082722473878000_2010.dec15_1.bcr0920103371.7","unstructured":"Product Information \u00e2\u0080\u0093 Epistatus. Buccal midazolam maleate solution equivalent to midazolam base 10 mg in 1 ml. Special Products Limited. http:\/\/www.phebra.com.au\/data\/products\/SOL041-pi.pdf (accessed 21 September 2010)."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.09.2010.3371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:47:48Z","timestamp":1756360068000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.09.2010.3371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":7,"alternative-id":["10.1136\/bcr.09.2010.3371"],"URL":"https:\/\/doi.org\/10.1136\/bcr.09.2010.3371","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2010]]}}}