{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:10:03Z","timestamp":1756293003386,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 47-year-old Filipino woman presented with goitre of 3 months\u2019 duration. She had no symptoms of thyrotoxicosis or hypothyroidism. Her thyroid was diffusely enlarged. Thyrotropin was elevated and free thyroxine was low. Ultrasound revealed slightly enlarged thyroid with diffuse parenchymal disease. Antithyroid peroxidase antibody was elevated. She was started on levothyroxine at 1.6 mcg\/kg body weight\/day and dose was adjusted to maintain the thyrotropin level within normal limits. Four years after the diagnosis of Hashimoto\u2019s thyroiditis was made, the patient started to experience malaise, generalised weakness and fatigue. Functional screening for other autoimmune endocrinopathy was done. Fasting 8 a.m serum cortisol was noted to be markedly decreased. She was diagnosed with autoimmune polyglandular syndrome type 2 (Schmidt syndrome). Physiologic dose of prednisone was started which afforded significant improvement in the patient\u2019s symptoms. The patient is on regular follow-up and clinically well.<\/jats:p>","DOI":"10.1136\/bcr.09.2011.4766","type":"journal-article","created":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T06:28:51Z","timestamp":1326263331000},"page":"bcr0920114766","source":"Crossref","is-referenced-by-count":1,"title":["A Filipino woman with autoimmune polyglandular syndrome: Table 1"],"prefix":"10.1136","volume":"2012","author":[{"given":"Cristina Vianzon","family":"Jaring","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Luisa Cecilia","family":"Rivera-Arkoncel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances Lina","family":"Lantion-Ang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,1,11]]},"reference":[{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021845"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.2","unstructured":"Jameson J De Groot L . Endocrinology, Adult and Pediatric. Sixth edition. Philadelphia, PA: Saunders 2010."},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.3","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.amjmed.2009.06.030","article-title":"Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease","volume":"123","author":"Boelaert","year":"2010","journal-title":"Am J Med"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.4","first-page":"605","article-title":"Polyglandular autoimmune syndrome: current concepts","volume":"138","author":"Meyerson","year":"1988","journal-title":"CMAJ"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2009.01.007"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2004.02561.x"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.7","unstructured":"Henderson K Baranski T Bickel P . Endocrinology Subspecialty Consult. Second edition. Saint Louis, Missouri: Washington University School of Medicine 2009."},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2009.02091.x"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra030158"},{"key":"2025082703421330000_2012.jan10_1.bcr0920114766.10","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-0044"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.09.2011.4766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:42:19Z","timestamp":1756291339000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.09.2011.4766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,11]]},"references-count":10,"alternative-id":["10.1136\/bcr.09.2011.4766"],"URL":"https:\/\/doi.org\/10.1136\/bcr.09.2011.4766","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012,1,11]]}}}