{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T15:40:01Z","timestamp":1745595601867,"version":"3.40.4"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>The use of 0.5 mg\/0.05 ml of ranibizumab intracamerally, to induce regression of iris neovascularisation in a non-diabetic patient, is reported. A 55-year-old Malay man presented with left eye rubeosis and hyphaema secondary to ischaemic remnant retinal flap in his silicone filled pseudophakic eye. Regression of rubeosis and resolution of hyphaema was noted within 4 days of injection of intracameral ranibizumab, allowing repeat vitrectomy to be performed without much bleeding, thus facilitating removal of his intraocular lens and laser to remaining flap. One month postoperatively he remained comfortable with counting fingers vision similar to the pre-hyphaema period.<\/jats:p>","DOI":"10.1136\/bcr.10.2009.2398","type":"journal-article","created":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T05:27:46Z","timestamp":1265002066000},"page":"bcr1020092398","source":"Crossref","is-referenced-by-count":0,"title":["Intracameral injection of ranibizumab caused regression of iris neovascularisation and clearance of hyphaema in a non-diabetic patient with ischaemic remnant retinal flap in a silicone filled eye"],"prefix":"10.1136","volume":"2010","author":[{"given":"Mae-Lynn Catherine","family":"Bastion","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,1,31]]},"reference":[{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90017-9"},{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.2","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1097\/IAE.0b013e318134eecd","article-title":"Pharmacokinetics and retinal distribution of ranibizumab, a humanized antibody fragment directed against VEGF-A, following intravitreal administration in rabbits","volume":"27","author":"Gaudreault","year":"2007","journal-title":"Retina"},{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1177\/112067210801800214","article-title":"Intracameral Avastin dramatically resolves iris neovascularisation and reverses neovascular glaucoma","volume":"18:2","author":"Chalam","year":"2008","journal-title":"Eur J Ophthalmol"},{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.4","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.1365-2125.2008.03278.x","article-title":"Intravitreal bevacizumab (Avastin(R)) injection for neovascular glaucoma: a survey on 23 cases throughout 12-month follow-up","volume":"66","author":"Costagliola","year":"2008","journal-title":"Br J Clin Pharmacol"},{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.5","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1111\/j.1442-9071.2007.01632.x","article-title":"Rapid improvement of radiation-induced neovascular glaucoma and exudative retinal detachment after a single intravitreal ranibizumab injection","volume":"35","author":"Dunavoelgyi","year":"2007","journal-title":"Clin Experiment Ophthalmol"},{"key":"2025042508260234000_2010.feb02_1.bcr1020092398.6","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318180e572"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.10.2009.2398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T15:26:08Z","timestamp":1745594768000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.10.2009.2398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":6,"alternative-id":["10.1136\/bcr.10.2009.2398"],"URL":"https:\/\/doi.org\/10.1136\/bcr.10.2009.2398","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2010]]}}}