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This article will review the pathophysiology and treatment options of SCA focusing the complications of leg ulcers, priapism, cholelithiasis and retinopathy. The case study of a 14-year-old boy is used to present a management challenge of multiple SCA-related complications.<\/jats:p>","DOI":"10.1136\/bcr.11.2011.5146","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T08:08:23Z","timestamp":1335773303000},"page":"bcr1120115146","source":"Crossref","is-referenced-by-count":2,"title":["An adolescent with sickle cell anaemia experiencing disease-related complications: priapism and leg ulcer \u2013 a management challenge"],"prefix":"10.1136","volume":"2012","author":[{"given":"Alexandra","family":"Vasconcelos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Rita","family":"Prior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anabela","family":"Ferr\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anabela","family":"Morais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,4,30]]},"reference":[{"key":"2025082723023594000_2012.apr28_1.bcr1120115146.1","unstructured":"WHO [Internet]. 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