{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:10:09Z","timestamp":1756368609224,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 31-year-old hypertensive woman was admitted to hospital with palpitations. Her hypertension was treated with bendroflumethiazide, which had been increased from 2.5 to 5 mg daily by her general practitioner about 18 months prior to her admission. She was also on ramipril 10 mg once daily. There were no abnormal findings on examination, and a 12-lead ECG showed sinus rhythm, rate 75, with Q waves in leads V1\u2013V2. Telemetry (over 24 h) showed ventricular bigeminy when she had her typical palpitations. Her admission serum sodium and potassium concentrations were 132 and 3.4 mmol\/l, respectively. Immediately prior to planned discharge the following day, she experienced paraesthesiae, weakness, confusion and seizures accompanied by 10 s asystole on the ECG monitor. Her serum sodium had fallen to 120 mmol\/l and potassium to 2.3 mmol\/l. Bendroflumethiazide and ramipril were discontinued and the patient was restricted to fluids of 1.5 l\/24 h. She also received potassium supplements. Her serum sodium concentration rose to normal over 6 days, and she was discharged on feeling well.<\/jats:p>","DOI":"10.1136\/bcr.12.2010.3594","type":"journal-article","created":{"date-parts":[[2011,5,17]],"date-time":"2011-05-17T06:43:29Z","timestamp":1305614609000},"page":"bcr1220103594","source":"Crossref","is-referenced-by-count":1,"title":["Life-threatening hyponatraemia: Figure 1"],"prefix":"10.1136","volume":"2011","author":[{"given":"Emmanuel Eroume A","family":"Egom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth Y-K","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew L","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,5,17]]},"reference":[{"key":"2025082800333820000_2011.may15_1.bcr1220103594.1","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1681\/ASN.V541106","article-title":"Increased susceptibility to thiazide-induced hyponatremia in the elderly.","volume":"5","author":"Clark","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.2","doi-asserted-by":"publisher","DOI":"10.1159\/000013496"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03460240051027"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.2.601"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.5","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg157"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.6","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1982.31"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1001458"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7176.2008.08126.x"},{"key":"2025082800333820000_2011.may15_1.bcr1220103594.9","doi-asserted-by":"publisher","DOI":"10.1159\/000086019"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.12.2010.3594","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:33:49Z","timestamp":1756366429000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.12.2010.3594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,17]]},"references-count":9,"alternative-id":["10.1136\/bcr.12.2010.3594"],"URL":"https:\/\/doi.org\/10.1136\/bcr.12.2010.3594","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2011,5,17]]}}}