{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:51:32Z","timestamp":1756385492311,"version":"3.40.4"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 51-year-old lady was referred to our clinic because of severe hypertension; blood pressure 214\/119 mm Hg despite treatment with an angiotensin receptor antagonist and a calcium channel blocker. Her initial laboratory results showed hypokalaemic alkalosis with normal urea and creatinine levels. Her 24-h urinary sodium excretion was markedly elevated at 244 mmol (equivalent to a daily intake of approximately 16 g of salt). Hyperaldosteronism was suspected but her plasma aldosterone level was subsequently found to be normal. On further questioning, the patient admitted to eating considerable amounts of salted liquorice and a diagnosis of acquired apparent mineralocorticoid excess was made. Liquorice has a well-known mineralocorticoid activity as it inhibits the action of 11\u03b2-hydroxysteroid dehydrogenase 2 and can induce mineralocorticoid hypertension. After stopping eating the salted liquorice, the patient\u2019s blood pressure quickly normalised and all her antihypertensive medications were stopped.<\/jats:p>","DOI":"10.1136\/bcr.12.2011.5336","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T14:19:33Z","timestamp":1330438773000},"page":"bcr1220115336","source":"Crossref","is-referenced-by-count":6,"title":["A salty cause of severe hypertension"],"prefix":"10.1136","volume":"2012","author":[{"given":"Elena Sanchez","family":"Ruiz-Granados","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Shouls","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Sainsbury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarek","family":"Antonios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,2,28]]},"reference":[{"key":"2025042701351551000_2012.feb25_1.bcr1220115336.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02775.x"},{"key":"2025042701351551000_2012.feb25_1.bcr1220115336.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.04.015"},{"key":"2025042701351551000_2012.feb25_1.bcr1220115336.3","doi-asserted-by":"publisher","DOI":"10.1161\/hy1101.096112"},{"key":"2025042701351551000_2012.feb25_1.bcr1220115336.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60514-6"},{"key":"2025042701351551000_2012.feb25_1.bcr1220115336.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)01463-8"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr.12.2011.5336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:35:24Z","timestamp":1745742924000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr.12.2011.5336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,28]]},"references-count":5,"alternative-id":["10.1136\/bcr.12.2011.5336"],"URL":"https:\/\/doi.org\/10.1136\/bcr.12.2011.5336","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012,2,28]]}}}