{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:53:22Z","timestamp":1793332402733,"version":"4.5.0"},"reference-count":21,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Fundamental Research Funds of the State Key Laboratory of Ophthalmology","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]},{"name":"Sun Yat-Sen University Clinical Research 5010 Program","award":["2014016"],"award-info":[{"award-number":["2014016"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2022,10,31]]},"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the efficacy and safety of anterior segment reconstruction (ASR) in congenital fibrovascular pupillary membrane-induced secondary glaucoma (CFPMSG) basing ultrasound biomicroscopy (UBM) classification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This ambispective cohort study enrolled patients with CFPMSG who underwent ASR between January 2014 and September 2020. Comprehensive ophthalmic examinations and UBM were performed before surgery and postoperatively. The patients were classified into three types according to the UBM configurations. Anterior chamber recovery (ACR) was defined as deepening in anterior chamber (\u22651.5\u2009mm all through final follow-up (FFU), while success following ASR was defined as ACR and intraocular pressure (IOP)\u226421\u2009mm Hg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>25 eyes of 25 patients underwent ASR (average age at operation 5.8\u00b15.0 months, 48% girls) with FFU 15.8\u00b116.9 months. Enrolled subjects were classified into type \u2160 (11 eyes), type \u2161 (11 eyes) and type \u2162 (3 eyes). After ASR, 23 eyes (92%) achieved ACR, and the mean ACD increased in all groups (p=0.006, &lt;0.001\u2009and 0.003, respectively). Eyes with types \u2160 and \u2161 demonstrated a reduction of IOP (p=0.009\u2009and 0.002, respectively). ASR success rate was highest in type \u2160 (72.9%) compared with types \u2161 and \u2162 (18.2% and 0%, respectively; p=0.011). ASR led to decreased number of antiglaucoma medications for type \u2160 CFPMSG at FFU (p=0.016). No vision-threatening postoperative complications occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ASR for CFPMSG results in increased ACD and improvement in IOP. Postoperative IOP control was best in type \u2160 CFPMSG but not as effective in types \u2161 and \u2162. UBM-based classification helps to predict the surgical outcome of ASR in CFPMSG.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2022-321762","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T13:20:16Z","timestamp":1668518416000},"page":"65-70","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Use of ultrasound biomicroscopy to predict the outcome of anterior segment reconstruction in congenital fibrovascular pupillary membrane with secondary glaucoma"],"prefix":"10.1136","volume":"108","author":[{"given":"Yingting","family":"Zhu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, 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