{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:19:59Z","timestamp":1789060799904,"version":"build-2803163510"},"reference-count":33,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"collaborative research project with Essilor International","award":["95016010"],"award-info":[{"award-number":["95016010"]}]},{"name":"collaborative research project with Essilor International","award":["95020005"],"award-info":[{"award-number":["95020005"]}]},{"name":"Medical and Health Science and Technology Project of Zhejiang Provincial Health Commission of China","award":["2022PY072"],"award-info":[{"award-number":["2022PY072"]}]},{"name":"Basic Scientific Research Project of Wenzhou","award":["Y2020343"],"award-info":[{"award-number":["Y2020343"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2022,9,7]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Spectacle lenses with highly aspherical lenslets (HAL) and slightly aspherical lenslets (SAL) showed effective myopia control. This study was to investigate their effects on macular choroidal thickness (ChT) in myopic children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Exploratory analysis from a 2-year, double-masked, randomised trial. 170 children aged 8\u201313 years with myopia between \u22120.75D and \u22124.75D, astigmatism of 1.50D or less, and anisometropia of 1.00D or less were recruited. Participants were randomly assigned in a 1:1:1 ratio to receive HAL, SAL or single vision spectacle lenses (SVL). The subfoveal, parafoveal and perifoveal ChT were evaluated every 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>154 participants completed all examinations. The ChT showed significant changes over time in all three groups in all regions (all p&lt;0.05). The ChTs continuously decreased in the SVL group (ranging from \u221220.75 (SD 22.34) \u03bcm to \u221212.18 (22.57) \u03bcm after 2\u2009years in different regions). Compared with the SVL group, ChT in the SAL group decreased less (ranging from \u221216.49 (21.27) \u03bcm to \u22125.29 (18.15) \u03bcm). In the HAL group, ChT increased in the first year and then decreased in the second year (ranging from \u22120.30 (27.54) \u03bcm to 8.92 (23.97) \u03bcm after two years). The perifoveal ChT decreased less than the parafoveal ChT, and the superior region decreased the least.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The ChT of the macula decreased after 2 years of myopia progression with SVL. Wearing spectacle lenses with aspherical lenslets reduced or abolished the ChT thinning and HAL had a more pronounced effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>ChiCTR1800017683.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2022-321815","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T13:21:04Z","timestamp":1664284864000},"page":"1806-1811","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":39,"title":["Effect of spectacle lenses with aspherical lenslets on choroidal thickness in myopic children: a 2-year randomised clinical 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