{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:57:02Z","timestamp":1787731022798,"version":"build-2784847793"},"reference-count":35,"publisher":"BMJ","issue":"2","funder":[{"name":"the Fundamental Research Funds of the State Key Laboratory of Ophthalmology","award":["83000-32030003"],"award-info":[{"award-number":["83000-32030003"]}]},{"name":"Global STEM Professorship Scheme","award":["P0046113"],"award-info":[{"award-number":["P0046113"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82301249"],"award-info":[{"award-number":["82301249"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Science and Technology Projects in Guangzhou","award":["SL2024A04J01756"],"award-info":[{"award-number":["SL2024A04J01756"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2024,7,13]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate the characteristics of myopic maculopathy among highly myopic Chinese children and adolescents and explore its associated risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Children and adolescents aged 7\u201317 years with spherical equivalent (SE) \u2264 \u22126.00 dioptres (D) were recruited. Myopic maculopathy was categorised based on the International Meta-Analysis of Pathological Myopia Classification. The extent of diffuse choroidal atrophy (DCA) was classified using Early Treatment Diabetic Retinopathy Study grid (ETDRS). The area of DCA was categorised into three classes relative to optic disk area (DA): A1 (\u22641\u2009DA), A2 (1 to \u22645\u2009DA) and A3 (5 to \u226410\u2009DA). Logistic regression was used to identify risk factors associated with myopic maculopathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 425 participants aged 13.66\u00b12.67 years, the proportions of tessellated fundus and DCA were 11.76% and 12.24%, and no more severe fundus lesions or \u2018plus\u2019 lesions. The proportion of DCA was 27.03% in children under 11, significantly higher than the 9.12% observed in those aged 11 and older (p&lt;0.001). The percentages of DCA involving the outer, middle and central circles of the ETDRS grid were 42.31%, 55.77% and 1.92%. Myopic maculopathy was significantly associated with younger age (p&lt;0.001), longer axial length (AL; p&lt;0.001) and larger \u03b2-zone peripapillary atrophy (\u03b2-PPA; p=0.012).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In highly myopic children and adolescents, myopic maculopathy predominantly manifested as DCA (12.24%), with no cases of worse myopic maculopathy or \u2018plus\u2019 lesions. Younger age, longer AL and larger \u03b2-PPA were risk factors for myopic maculopathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2023-324430","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T13:21:10Z","timestamp":1722000070000},"page":"257-263","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Characteristics of myopic maculopathy in Chinese children and adolescents with high 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