{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T19:24:45Z","timestamp":1782156285848,"version":"3.54.5"},"reference-count":21,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2024,4,14]]},"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>There is limited data regarding the morbidity and progression to primary angle closure glaucoma in those presenting with acute primary angle closure (APAC) in the UK. We aim to report on the vision and intraocular pressure (IOP) outcomes and treatment required after an APAC episode and to identify any risk factors that could predict worse outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective observational case series review including 117 consecutive patients (121 eyes) attending Moorfields Eye Hospital, at a tertiary referral unit in the UK, with APAC was performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Most patients (73%) had visual acuities of \u22656\/12, meeting the UK driving standard, at the final follow-up. Only 15% (17 eyes) had severe visual impairment, as defined by the WHO, in the affected eye, of which 6.6% (eight eyes) were due to glaucoma. The delayed presentation was linked to a higher need for further medical treatment (OR=2.83, 95% CI 1.09 to 7.40, p=0.03). Patients who underwent phacoemulsification were at lower risk of having blindness in the affected eye (OR 0.18, 95% CI 0.05 to 0.69, p=0.01), having elevated IOP (OR 0.10, 95% CI 0.01 to 0.75, p=0.02) or requiring further medical treatment (OR 0.34, 95% CI 0.12 to 0.99, p=0.04). Older age (OR 1.26, 95% CI 1.08 to 1.48, p&lt;0.01) was associated with worse visual outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>APAC causes low long-term visual and treatment morbidity in this largely Caucasian patient group in the UK. Phacoemulsification as a treatment may enhance visual outcomes and reduce the need for further IOP-lowering treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bjo-2023-324748","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T13:20:15Z","timestamp":1715606415000},"page":"1659-1664","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Long-term outcomes after acute primary angle closure: case series from Moorfields Eye Hospital, UK"],"prefix":"10.1136","volume":"108","author":[{"given":"Sana","family":"Hamid","sequence":"first","affiliation":[{"name":"Glaucoma Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2614-0234","authenticated-orcid":false,"given":"Francesco","family":"Matarazzo","sequence":"additional","affiliation":[{"name":"Glaucoma Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK"},{"name":"University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Sun","sequence":"additional","affiliation":[{"name":"NIHR Moorfields Biomedical Research Centre, London, Greater London, UK"},{"name":"UCL Institute of Ophthalmology, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandika","family":"Baboolal","sequence":"additional","affiliation":[{"name":"Glaucoma Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK"},{"name":"James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, Norfolk, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhakshi","family":"Muhundhakumar","sequence":"additional","affiliation":[{"name":"Glaucoma Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4755-177X","authenticated-orcid":false,"given":"Paul J","family":"Foster","sequence":"additional","affiliation":[{"name":"NIHR Moorfields Biomedical Research Centre, London, Greater London, UK"},{"name":"UCL Institute of Ophthalmology, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,5,13]]},"reference":[{"key":"2025071603351110000_108.12.1659.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ophtha.2015.10.049","article-title":"Primary angle closure preferred practice pattern\u00ae guidelines","volume":"123","author":"Prum","year":"2016","journal-title":"Ophthalmology"},{"key":"2025071603351110000_108.12.1659.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2003.12.061"},{"key":"2025071603351110000_108.12.1659.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.05.013"},{"key":"2025071603351110000_108.12.1659.4","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1975.01010020277006"},{"key":"2025071603351110000_108.12.1659.5","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1982.01030030927004"},{"key":"2025071603351110000_108.12.1659.6","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/eye.2011.361","article-title":"Cyclodiode laser in the treatment of acute angle closure","volume":"26","author":"Manna","year":"2012","journal-title":"Eye (Lond)"},{"key":"2025071603351110000_108.12.1659.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.10.033"},{"key":"2025071603351110000_108.12.1659.8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100160606014"},{"key":"2025071603351110000_108.12.1659.9","unstructured":"Version: 2010. chapter VII H54.9. 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