{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T09:49:55Z","timestamp":1793353795805,"version":"4.5.0"},"reference-count":34,"publisher":"BMJ","issue":"1","funder":[{"name":"Science and Technology Program of Guangzhou, China","award":["202201020362"],"award-info":[{"award-number":["202201020362"]}]},{"name":"Science and Technology Program of Guangzhou, China","award":["2024A03J00515"],"award-info":[{"award-number":["2024A03J00515"]}]},{"name":"Lumitin Vision to Brightness Research Funding for the Young and middle-aged Ophthalmologists","award":["BCF-KH-YK-20230803-03"],"award-info":[{"award-number":["BCF-KH-YK-20230803-03"]}]},{"name":"Innovative Clinical Technique of Guangzhou","award":["2024P-GX02"],"award-info":[{"award-number":["2024P-GX02"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2024,5,10]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate the effect of preretinal tractional structures (PTS) and posterior scleral structures (PSS) on myopic traction maculopathy (MTM) progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study included 185 fellow highly myopic eyes of 185 participants who underwent surgery for MTM. PTS included epiretinal membrane, incomplete posterior vitreous detachment and their combination. PSS included posterior staphyloma and dome-shaped macula (DSM). The MTM stage was graded according to the Myopic Traction Maculopathy Staging System. Optical coherence tomography was used to identify MTM progression, defined as an upgrade of MTM. The Kaplan-Meier method with log-rank test was used to assess MTM progression over the 3-year follow-up period. Risk factors for progression were identified using Cox regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MTM progression was observed in 48 (25.9%) eyes. Three-year progression-free survival (PFS) rates for eyes with PTS, staphyloma and DSM were 53.7%, 58.2% and 90.7%, respectively. Eyes with PTS and staphyloma exhibited lower 3-year PFS rates than those without PTS or staphyloma (<jats:italic>P<\/jats:italic><jats:sub>log-rank test<\/jats:sub>=0.002 and &lt;0.001), while eyes with DSM had a higher 3-year PFS rate than eyes without DSM (<jats:italic>P<\/jats:italic><jats:sub>log-rank test<\/jats:sub>=0.01). Multivariate Cox regression analysis showed that PTS (HR, 3.23; p&lt;0.001) and staphyloma (HR, 7.91; p&lt;0.001) were associated with MTM progression, whereas DSM (HR, 0.23; p=0.046) was a protective factor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both PTS and PSS play a critical role in the progression of MTM. Addressing these factors can aid in the management of MTM.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bjo-2024-325274","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T17:20:34Z","timestamp":1716398434000},"page":"83-88","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Risk factors and patterns for progression of fellow-eye myopic traction maculopathy: a 3-year retrospective cohort 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