{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:39:57Z","timestamp":1791265197942,"version":"4.1.0"},"reference-count":36,"publisher":"BMJ","issue":"7","funder":[{"name":"Key R&D Program of China","award":["2022YFC2502800"],"award-info":[{"award-number":["2022YFC2502800"]}]},{"name":"The Science and Technology Program of Sichuan Province","award":["2020YJ0289"],"award-info":[{"award-number":["2020YJ0289"]}]},{"name":"Chongqing Natural Research Foundation","award":["2018jcyjAX0034"],"award-info":[{"award-number":["2018jcyjAX0034"]}]},{"name":"Chongqing Natural Research Foundation","award":["CSTB2022NSCQ-MSX0077"],"award-info":[{"award-number":["CSTB2022NSCQ-MSX0077"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2022CXA016"],"award-info":[{"award-number":["2022CXA016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670860"],"award-info":[{"award-number":["81670860"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101139"],"award-info":[{"award-number":["82101139"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["GZ2022094"],"award-info":[{"award-number":["GZ2022094"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2025,2,12]]},"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report the 2-year effective and safety profile of integrated phacoemulsification with intraocular lens implantation (PEI), goniosynechialysis (GSL) and 120\u00b0 goniotomy (GT) in advanced primary angle-closure glaucoma (PACG) and cataracts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Multicentre prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>201 eyes of 196 patients who received combined PEI+GSL+\u2009GT were assessed at baseline and re-evaluated at days 1, 7, and at 1, 3, 6, 12 and 24 months postsurgery. The intraocular pressure (IOP), the number of topical hypotensive medications, surgical complications and achievements of surgery success were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All participants were followed up for a 2-year period. The average IOP declined from 33.0\u00b110.7\u2009mm Hg to 13.6\u00b12.9\u2009mm Hg, and the number of topical hypotensive medication decreased from an average of 2.4 types to 0.4 at month 24. For the safety profile, the major complications were hyphema (n=14, 7.0%), IOP spike (n=9, 4.9%) and transit corneal oedema (n=23, 11.4%). The complete success was achieved in 72.6% of the eyes (146 out of 201), and the qualified success rate was 91.5% (184 out of 201). Only one eye required tube shunt surgery while no one developed severe vision-threatening complications. The best-corrected visual acuity increased from 0.80\u00b11.08\u2009to 0.54\u00b10.78 LogMAR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PEI+GSL+GT is shown to be effective and safe in treating advanced PACG with cataract over a 2-year follow-up period. The combined surgery may be considered as an alternative for patients with advanced PACG.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2024-325375","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T07:10:25Z","timestamp":1741331425000},"page":"770-774","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Two-year outcome of phacogoniotomy for advanced primary angle-closure glaucoma with cataracts: a multicentre study"],"prefix":"10.1136","volume":"109","clinical-trial-number":[{"clinical-trial-number":"nct04878458","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Yunhe","family":"Song","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular 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