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Linear models were used to investigate the relationship between CH change and RNFL thickness change over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 123 eyes, 30 eyes (24.4%, 42.9\u00b19.3 years, 36.7% males) demonstrated RNFL loss (93 eyes no progression, 44.4\u00b19.6 years, 30.1% males). No statistically significant difference was found in IOP, but significantly greater decrease in CH was noted in the progression group (\u22122.525% baseline (95%\u2009CI \u22124.974 to \u22120.076) vs 1.068% baseline (95%\u2009CI, \u22120.322 to 2.458); p=0.013). Relative CH change was greater for more advanced stage of OAG among the progression group. Patients with the greatest relative CH decrease over time was 1.7 times more likely to present RNFL loss (HR 1.705, 95%\u2009CI 1.113 to 2.611, p=0.014).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Longitudinal decrease in CH over time was greater in those showing structural progression than those without progression among medically controlled, early-to-moderate OAG with a history of LRS. Decrease in CH was significantly associated with faster RNFL loss. Larger CH changes indicate a higher risk of OAG progression in those with a history of LRS.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bjo-2024-326405","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T18:20:15Z","timestamp":1736792415000},"page":"668-674","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal corneal hysteresis changes predict structural progression in medically controlled, early-to-moderate, open-angle glaucoma with a history of refractive surgery"],"prefix":"10.1136","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1585-168X","authenticated-orcid":false,"given":"Jihei Sara","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8421-5636","authenticated-orcid":false,"given":"Hyoung Won","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8373-9999","authenticated-orcid":false,"given":"Chan Yun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3834-7953","authenticated-orcid":false,"given":"Sang Yeop","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"key":"2025053005152062000_109.6.668.1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32835cef31"},{"key":"2025053005152062000_109.6.668.2","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12347"},{"key":"2025053005152062000_109.6.668.3","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305962"},{"key":"2025053005152062000_109.6.668.4","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19615"},{"key":"2025053005152062000_109.6.668.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2022.11.030"},{"key":"2025053005152062000_109.6.668.6","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-022-02309-x"},{"key":"2025053005152062000_109.6.668.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.01.032"},{"key":"2025053005152062000_109.6.668.8","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307428"},{"key":"2025053005152062000_109.6.668.9","doi-asserted-by":"crossref","first-page":"e627","DOI":"10.1111\/aos.12726","article-title":"Change in corneal hysteresis over time in normal, glaucomatous and diabetic eyes","volume":"93","author":"Hussnain","year":"2015","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"2025053005152062000_109.6.668.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.11.010"},{"key":"2025053005152062000_109.6.668.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.10.044"},{"key":"2025053005152062000_109.6.668.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.02.020"},{"key":"2025053005152062000_109.6.668.13","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1167\/iovs.63.3.28","article-title":"Systemic Arterial Stiffness Is Associated With Structural Progression in Early Open-Angle Glaucoma","volume":"63","author":"Lee","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"2025053005152062000_109.6.668.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2019.03.016"},{"key":"2025053005152062000_109.6.668.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2022.11.009"},{"key":"2025053005152062000_109.6.668.16","doi-asserted-by":"crossref","unstructured":"Kaushik S , Pandav SS , Banger A , et al . 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