{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:09:05Z","timestamp":1788930545103,"version":"build-2803163510"},"reference-count":36,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2025,7,29]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Persistent full-thickness macular holes (FTMHs) following primary surgery represent a therapeutic challenge. Various surgical treatment approaches have been proposed. This study evaluates anatomical and functional outcomes of a temporary silicone oil tamponade in persistent FTMH in a larger cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a retrospective multicentre study, we included consecutive patients with persistent FTMH following vitrectomy with inner limiting membrane peeling and gas tamponade who were treated by a temporary silicone oil tamponade. FTMH morphology in optical coherence tomography, minimum linear diameter (MLD), closure rate and best-corrected visual acuity (BCVA) change were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 102 eyes of 102 consecutive patients were included. Median duration of silicone oil tamponade was 16.6 weeks (interquartile range (IQR) 12.0\u201322.1). Closure of the macular hole (flat\/closed configuration) was achieved in 92.2% of eyes. Median BCVA improved significantly from 1.00 logMAR (IQR 0.70\u20131.15) to 0.70 logMAR (IQR 0.49\u20131.00; p&lt;0.0001). Mean preoperative MLD was 460.7\u2009\u00b5m (\u00b1194.2; range 136\u20131016), with significantly higher MLD in eyes with unsuccessful (614.4\u2009\u00b5m\u00b1250.4) compared with successful (446.9\u2009\u00b5m\u00b1183.9; p=0.019) silicone oil treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Treatment of persistent FTMH with a temporary conventional silicone oil tamponade without retinal manipulation or postoperative positioning results in a high anatomical success rate and significant mean BCVA improvement. Success rate decreases with higher FTMH size.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2024-326582","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T17:23:23Z","timestamp":1757352203000},"page":"318-323","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Temporary silicone oil tamponade for persistent macular holes: a multicentre study"],"prefix":"10.1136","volume":"110","author":[{"given":"Verena","family":"Sch\u00f6neberger","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany"},{"name":"Department of Ophthalmology, University Medical Center Rostock, Rostock, Germany"},{"name":"Department of Ophthalmology, Medical Faculty and University Hospital D\u00fcsseldorf, Heinrich Heine University D\u00fcsseldorf, D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thea","family":"Hofmann","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeany Q","family":"Lammert","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0936-2414","authenticated-orcid":false,"given":"Leonie","family":"Menghesha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8019-9272","authenticated-orcid":false,"given":"Frank 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