{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:03:09Z","timestamp":1790071389401,"version":"4.0.1"},"reference-count":28,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2026,1,16]]},"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report long-term outcomes of Aurolab aqueous drainage implant (AADI) surgery in adults with refractory glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective, non-comparative, interventional case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Case records of patients aged &gt;18 years who underwent AADI surgery between 2012 and 2018 and had &gt;5 years of follow-up were reviewed. Intraocular pressure (IOP), visual acuity, number of IOP-lowering medications, complications and reoperations were recorded at baseline and at 1 day, 1 month, 3 months, 6 months, 1 year and annually thereafter. Failure was defined as IOP&gt;21 mmHg or reduced&lt;20% below the baseline, IOP\u22645 mmHg, reoperation for glaucoma or a complication or loss of light perception vision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 282 eyes from 282 patients. Age (mean\u00b1SD) was 45.2\u00b112.3 years, and 191 (68%) were men. Secondary angle closure glaucoma was the most common aetiologic group (30%), followed by secondary open angle glaucoma (25%) and primary open angle glaucoma (22%). IOP (mean\u00b1SD) decreased from 33.1\u00b110.4 mmHg at baseline to 16.5\u00b16.5 mmHg at 5 years. The cumulative probability of failure was 34.4% (95% CI 29.2 to 40.3) at 5 years. Corneal endothelial decompensation was the most common complication occurring in 32 eyes (11%). Delayed hypotony was seen in only four eyes (1.4%). After adjusting for age, sex and previous trabeculectomy, eyes with secondary glaucoma had a 32% lower risk of failure (HR=0.68, 95% CI 0.50 to 0.94, p=0.02).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The AADI showed good control of IOP over 5 years, but corneal endothelial decompensation remains a concern.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2025-327124","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T18:20:19Z","timestamp":1769710819000},"page":"1183-1188","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Long-term outcomes of Aurolab aqueous drainage implant in adults with refractory glaucoma"],"prefix":"10.1136","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3728-2884","authenticated-orcid":false,"given":"George 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