{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T10:05:20Z","timestamp":1779271520270,"version":"3.51.4"},"reference-count":35,"publisher":"BMJ","issue":"6","funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2022-NR075402"],"award-info":[{"award-number":["RS-2022-NR075402"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00405287"],"award-info":[{"award-number":["RS-2024-00405287"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00562090"],"award-info":[{"award-number":["RS-2025-00562090"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Gangnam Severance Hospital","award":["3-2024-0002"],"award-info":[{"award-number":["3-2024-0002"]}]},{"name":"Gangnam Severance Hospital","award":["D-2023-0012"],"award-info":[{"award-number":["D-2023-0012"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2025,11,8]]},"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This retrospective, comparative study evaluated the long-term impact of pars plana vitrectomy (PPV) for epiretinal membrane (ERM) removal on glaucoma progression, focusing on the influence of glaucoma severity and adjunctive internal limiting membrane (ILM) peeling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 231 eyes from patients diagnosed with primary open-angle glaucoma and coexisting ERM were included. Participants were divided into two groups: 114 eyes underwent PPV for ERM removal (PPV group) and 117 eyes did not undergo surgery (non-PPV group). The PPV group was further subdivided based on glaucoma severity and ILM peeling. Functional and structural parameters were assessed over 4 years using visual field testing, intraocular pressure (IOP) measurement, and optical coherence tomography. Linear mixed models were used for statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The PPV group demonstrated a significant deterioration in mean deviation and visual field index, compared with the non-PPV group, over 4 years (p&lt;0.001). However, the rate of progression did not differ significantly based on glaucoma severity. Patients with severe glaucoma experienced a relatively greater functional burden. Adjunctive ILM peeling did not worsen functional or structural outcomes. IOP and medication use remained stable throughout the study period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While associated with long-term visual field decline, PPV for symptomatic ERM demonstrates a consistent impact on glaucoma progression, irrespective of baseline disease severity. ILM peeling does not confer additional risk. These findings support individualised surgical decision-making based on patient symptoms rather than glaucoma stage alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2025-327683","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T18:20:29Z","timestamp":1764786029000},"page":"643-650","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of epiretinal membrane surgery on glaucoma progression: influence of glaucoma severity and internal limiting membrane peeling"],"prefix":"10.1136","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2886-3048","authenticated-orcid":false,"given":"Heesuk","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunjo","family":"Jang","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine, seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8421-5636","authenticated-orcid":false,"given":"Hyoung Won","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8373-9999","authenticated-orcid":false,"given":"Chan Yun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wungrak","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"2026052002050986000_110.6.643.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.05.013"},{"key":"2026052002050986000_110.6.643.2","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-92971-w","article-title":"Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review","volume":"11","author":"Zhang","year":"2021","journal-title":"Sci Rep"},{"key":"2026052002050986000_110.6.643.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.08.009"},{"key":"2026052002050986000_110.6.643.4","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-014644","article-title":"Prevalence and risk factors of epiretinal membranes: a systematic review and meta-analysis of population-based studies","volume":"7","author":"Xiao","year":"2017","journal-title":"BMJ Open"},{"key":"2026052002050986000_110.6.643.5","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1007\/s10384-018-0581-x","article-title":"Comparison of visual acuity, metamorphopsia, and aniseikonia in patients with an idiopathic epiretinal membrane","volume":"62","author":"Tanikawa","year":"2018","journal-title":"Jpn J Ophthalmol"},{"key":"2026052002050986000_110.6.643.6","doi-asserted-by":"crossref","first-page":"81","DOI":"10.36299\/jkgs.2022.11.2.81","article-title":"The Effect of Epiretinal Membrane Peeling in Open Angle Glaucoma Patients with Epiretinal Membrane","volume":"11","author":"Seo","year":"2022","journal-title":"J Korean Glaucoma Soc"},{"key":"2026052002050986000_110.6.643.7","doi-asserted-by":"crossref","unstructured":"Bae KW , Kim DI , Hwang DD-J . n.d. 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