{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T14:57:30Z","timestamp":1782572250687,"version":"3.54.5"},"reference-count":29,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2025,7,29]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate clinical features and visual outcomes in macular pseudohole (MPH) and to investigate associations between visual acuity and optical coherence tomography (OCT) parameters in patients with MPH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed consecutive patients with MPH who underwent vitrectomy and were followed for at least 6 months after surgery. MPH was diagnosed based on spectral-domain OCT findings. Analysed factors included axial length, spherical equivalent, overlapping cases of epiretinal membrane foveoschisis (ERM-FS) and lamellar macular hole (LMH), presence of glaucoma, preoperative and postoperative best-corrected visual acuity (BCVA), presence of inner and outer retinal cysts, epiretinal proliferation (EP) and ellipsoid zone (EZ) disruption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study enrolled 76 eyes of 75 patients, with overlapping cases that included MPH+ERM\u2009FS (17 eyes), MPH+LMH (18 eyes) and MPH+ERM\u2009FS + LMH (3 eyes). BCVA significantly improved from 0.29\u00b10.25 preoperatively to 0.06\u00b10.17 postoperatively (p&lt;0.001). Preoperative BCVA and the presence of EP exhibited significant associations with worse postoperative BCVA (p&lt;0.0005\u2009and p&lt;0.05, respectively). Presence of EZ disruption at 3 and 6 months postoperatively was associated with worse postoperative BCVA (p&lt;0.001\u2009and p&lt;0.01, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There was significant improvement in patients with MPH after undergoing surgery. Current results suggest preoperative poor visual acuity, preoperative presence of EP and postoperative EZ disruption are negative prognostic factors for visual outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjo-2025-327808","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T02:15:42Z","timestamp":1754878542000},"page":"83-88","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical characteristics and visual outcome of patients with macular pseudohole"],"prefix":"10.1136","volume":"110","author":[{"given":"Kayano","family":"Shioda","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Nippon Medical School, Tokyo, 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