{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:26:16Z","timestamp":1756992376646},"reference-count":13,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1948,1,1]]},"DOI":"10.1136\/bjo.32.1.43","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"43-46","source":"Crossref","is-referenced-by-count":1,"title":["LOCAL SULPHONAMIDE THERAPY OF DENDRITIC ULCER"],"prefix":"10.1136","volume":"32","author":[{"given":"H. L.","family":"Hughes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"373","author":"KETTESY, A.-(Kreiker); der Hornhaut, Vollstandige Bindehautdeckung; etc., Klin","unstructured":"KETTESY, A.-(Kreiker): Vollstandige Bindehautdeckung der Hornhaut, etc., Klin. Monatsbl. f. Augenheilk., Vol. XC, p. 373,1933.","journal-title":"Monatsbl. f. Augenheilk., Vol. XC"},{"key":"ref_2","first-page":"138","article-title":"Behandlung des Ulcus serpens etc., Klin","author":"MIKLoS, A.","year":"1941","unstructured":"A. MIKLoS.-Behandlung des Ulcus serpens etc., Klin. Monatsbi. f. Augenheilk., Vol. CVII, p. 138, 1941.","journal-title":"Monatsbi. f. Augenheilk., Vol. CVII"},{"key":"ref_3","article-title":"die ges'","author":"f, L.A.W.A.E.T.Z.Zentralbl","year":"1943","unstructured":"LAWAETZ.-Zentralbl. f. die ges' Okhthal., 1943.","journal-title":"Okhthal"},{"key":"ref_4","article-title":"IN the early days of sulphonamide therapy Kleefeld","author":"Augenarztl, T.H.I.E.L.","year":"1942","unstructured":"THIEL.-Augenarztl. Operations. Thieme, 1942. IN the early days of sulphonamide therapy Kleefeld (1938) recorded favouirable results from the general administration of the drug in six cases of dendritic ulceration an-d in twenty cases of corneal herpes. Schmidand Saubermann (1942) likewise obtained satisfactory results in five out of twenty-one cases of herpes corneae. Most","journal-title":"Operations. Thieme; recorded favouirable results from the general administration of the drug in six cases of dendritic ulceration an-d in twenty cases of corneal herpes"},{"key":"ref_5","author":"for Publication, Received","year":"1947","unstructured":"Received for Publication, July 18, 1947."},{"key":"ref_6","article-title":"have had a less favotirable experience but Sorsby","volume-title":"has drawn attention to the value of local therapy in dendritic ulcer. He reported unexpectedly encouraging results from the intensive uise of local sulphonamide therapy in sixteen consecutive cases. Improvement was generally rapid and most eyes, though not fully cured, were symptomless within ten to fourteen days","author":"observers, however","year":"1944","unstructured":"observers, however, have had a less favotirable experience but Sorsby (1944) has drawn attention to the value of local therapy in dendritic ulcer. He reported unexpectedly encouraging results from the intensive uise of local sulphonamide therapy in sixteen consecutive cases. Improvement was generally rapid and most eyes, though not fully cured, were symptomless within ten to fourteen days."},{"key":"ref_7","article-title":"A Series of 16 cases Clinical features. Local therapy was employed in a series of sixteen consecutive cases seen during January-April, 1947. The clinical details are set forth in Table I. It will be noted that twelve cases out of sixteen responded to treatment, and that in six of these twelve cases, the response was particularly good. The cases showing a good response (Nos. 1-6 in Table I) showed the following features: (1) Morphologically the ulcers were all small, typical dendritic figures occupying an area about 1 X 1I mm. in an otherwise healthy looking cornea","unstructured":"A Series of 16 cases Clinical features.-Local therapy was employed in a series of sixteen consecutive cases seen during January-April, 1947. The clinical details are set forth in Table I. It will be noted that twelve cases out of sixteen responded to treatment, and that in six of these twelve cases, the response was particularly good. The cases showing a good response (Nos. 1-6 in Table I) showed the following features: (1) Morphologically the ulcers were all small, typical dendritic figures occupying an area about 1 X 1I mm. in an otherwise healthy looking cornea."},{"key":"ref_8","article-title":"Sensation was diminished in three cases, normal in two, and appeared relatively increased in one","unstructured":"Sensation was diminished in three cases, normal in two, and appeared relatively increased in one."},{"key":"ref_9","article-title":"The duration of the symptoms before treatment varied from","unstructured":"The duration of the symptoms before treatment varied from"},{"key":"ref_10","article-title":"in three remained","author":"Sensation was diminished in all cases, and","unstructured":"Sensation was diminished in all cases, and in three remained"},{"key":"ref_11","first-page":"14","article-title":"Soc. Beige d'Ofhtal. Vol","author":"KLEEFELD, G.","year":"1938","unstructured":"KLEEFELD, G. (1938)-Bull. Soc. Beige d'Ofhtal. Vol. LXXVI, p. 14.","journal-title":"LXXVI"},{"key":"ref_12","first-page":"65","volume":"Vol.","author":"S.C.H.M.I.D.; S.A.U.B.E.R.M.A.N.N.","year":"1942","unstructured":"SCHMID and SAUBERMANN, (1942)-Ophthatmologica, Vol. CIII, p. 65."},{"key":"ref_13","first-page":"75","author":"SORSBY, A.","year":"1944","unstructured":"SORSBY, A. (1944)-Trans. Ophthal. Soc. U.K., Vol. LXIV, p. 75.","journal-title":"LXIV"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bjo.32.1.43","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T20:00:35Z","timestamp":1601064035000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjo.32.1.43"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1948,1,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1948,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/bjo.32.1.43","relation":{},"ISSN":["0007-1161"],"issn-type":[{"value":"0007-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1948,1,1]]}}}