{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T16:11:11Z","timestamp":1768407071283,"version":"3.49.0"},"reference-count":37,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1984,3,1]]},"DOI":"10.1136\/bjo.68.3.167","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"167-173","source":"Crossref","is-referenced-by-count":27,"title":["Metastatic carcinoma of the iris simulating iridocyclitis."],"prefix":"10.1136","volume":"68","author":[{"given":"J. J.","family":"Woog","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Chess","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. K.","family":"Dueker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. G.","family":"Berson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Craft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"issue":"29 33","key":"ref_1","article-title":"acknowledged by Kreibig'0 and has subsequently been recognised by other investigators.3","volume-title":"Marked anterior uveitis occurring in this setting may result in an elevation of intraocular pressure,33 as in our patient, mimicking uveitic glaucoma. Intraocular inflammation secondary to anterior segment metastasis may be severe enough to prompt a clinical diagnosis of infectious endophthalmitis.28 Indeed a precise clinical diagnosis of iridocyclitis secondary to malignancy is often difficult, and the diagnosis may accordingly be delayed. In the study of Ferry and Font, for example, iridocyclitis occurred in 40% of patients with anterior segment involvement; disseminated malignancy was suspected initially in fewer than half of these patients.3 The development of hyphaema in association with iridocyclitis is, according to several authors,24 particularly suggestive of underlying malignancy, and this observation may be helpful in the early diagnosis of anterior segment metastasis","volume":"28","year":"24-26","unstructured":"acknowledged by Kreibig'0 and has subsequently been recognised by other investigators.3 24-26 28 29 33 34 Marked anterior uveitis occurring in this setting may result in an elevation of intraocular pressure,33 as in our patient, mimicking uveitic glaucoma. Intraocular inflammation secondary to anterior segment metastasis may be severe enough to prompt a clinical diagnosis of infectious endophthalmitis.28 Indeed a precise clinical diagnosis of iridocyclitis secondary to malignancy is often difficult, and the diagnosis may accordingly be delayed. In the study of Ferry and Font, for example, iridocyclitis occurred in 40% of patients with anterior segment involvement; disseminated malignancy was suspected initially in fewer than half of these patients.3 The development of hyphaema in association with iridocyclitis is, according to several authors,24 particularly suggestive of underlying malignancy, and this observation may be helpful in the early diagnosis of anterior segment metastasis."},{"key":"ref_2","article-title":"The value of paracentesis in the diagnosis of malignancy in the setting of iridocyclitis of uncertain aetiology was discussed by Remky in 196135 and by Morgan etal. in 1970.29 The latter authors described a","unstructured":"The value of paracentesis in the diagnosis of malignancy in the setting of iridocyclitis of uncertain aetiology was discussed by Remky in 196135 and by Morgan etal. in 1970.29 The latter authors described a"},{"key":"ref_3","first-page":"72","article-title":"Tumor metastasis to the eye. 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The biological behavior and pathological features of carcinoma metastatic to the eye and orbit. Trans Am Ophthalmol Soc 1973; 71: 373-425.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/archopht.1974.01010010286003","article-title":"Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases","volume":"92","author":"Ferry, A.P.; Font, R.L.","year":"1973","unstructured":"Ferry AP, Font RL. Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases. Arch Ophthalmol 1973; 92:276-86.","journal-title":"Arch Ophthalmol"},{"key":"ref_7","first-page":"427","article-title":"Application of millipore filtration technique to cytologic material","volume":"22","year":"1959","unstructured":"Delvecchio PR, DeWitt SH, Bovelli JI, Ward JR, Wood, TA Jr, Malmgren RA. Application of millipore filtration technique to cytologic material. 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