{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:25:52Z","timestamp":1789179952751,"version":"build-2803163510"},"reference-count":30,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1988,5,1]]},"DOI":"10.1136\/bjo.72.5.390","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"390-393","source":"Crossref","is-referenced-by-count":13,"title":["Alpha 1-antitrypsin and serum albumin in tear fluids in acute adenovirus conjunctivitis."],"prefix":"10.1136","volume":"72","author":[{"given":"A. K.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. S.","family":"Sarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. D.","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"1045","article-title":"Alpha-i antitrypsin deficiency","volume":"299","author":"Morse, J.O.","year":"1978","unstructured":"Morse JO. Alpha-i antitrypsin deficiency. N Engl J Med 1978; 299: 1045-8. a,-Antitrypsin andserum albumin in tearfluids in acute adenovirus conjunctivitis","journal-title":"N Engl J Med; Antitrypsin andserum albumin in tearfluids in acute adenovirus conjunctivitis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/archotol.1976.00780110075008","article-title":"Alpha-1 antitrypsin activity of the perilymph. Occurrence during progression of otospongiosis","volume":"102","author":"Chevance, L.G.; Causse, JR, Berges; J.","year":"1976","unstructured":"Chevance LG, Causse JR, Berges J. Alpha-1 antitrypsin activity of the perilymph. Occurrence during progression of otospongiosis. Arch Otolaryngol 1976; 102: 363-4.","journal-title":"Arch Otolaryngol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0009-8981(75)90217-X","article-title":"Alpha-1 antitrypsin in duodenal fluid and gall bladder bile","volume":"59","author":"Kyay-Myint, T.O.; Howell, A.M.; Murphy, G.M.","year":"1975","unstructured":"Kyay-Myint TO, Howell AM, Murphy GM. Alpha-1 antitrypsin in duodenal fluid and gall bladder bile. Clin Chim Acta 1975; 59: 51-4.","journal-title":"Clin Chim Acta"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1542\/peds.56.1.91","article-title":"Basic and clinical aspects of the alpha-1 antitrypsin","volume":"56","author":"Talamo, R.C.","year":"1975","unstructured":"Talamo RC. Basic and clinical aspects of the alpha-1 antitrypsin. Pediatrics 1975; 56: 91-9.","journal-title":"Pediatrics"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0016-5085(76)80506-9","article-title":"The current status of alpha-1 antitrypsin, a protease inhibitor in gastrointestinal diseases","volume":"70","author":"Sharp, H.L.","year":"1973","unstructured":"Sharp HL. The current status of alpha-1 antitrypsin, a protease inhibitor in gastrointestinal diseases. Gastroenterology 1973; 70: 611-21.","journal-title":"Gastroenterology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/274589a0","article-title":"Alpha-1 antitrypsin is an effector of immunologic stasis","volume":"274","author":"Arora, P.K.; Miller, H.C.; Aronson, L.D.","year":"1978","unstructured":"Arora PK, Miller HC, Aronson LD. Alpha-1 antitrypsin is an effector of immunologic stasis. Nature 1978; 274: 589-90.","journal-title":"Nature"},{"key":"ref_7","first-page":"759","article-title":"Corneal ulceration and the serum antiproteases","volume":"1","author":"Berman, M.B.; Barber, J.C.; Talamo, R.C.; Langley, C.E.","year":"1973","unstructured":"Berman MB, Barber JC, Talamo RC, Langley CE. Corneal ulceration and the serum antiproteases. I. alpha-1 antitrypsin. Invest Ophthalmol Vis Sci 1973; 12: 759-70.","journal-title":"I"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1755-3768.1983.tb01421.x","article-title":"Serum albumin, serum antiproteases and polymorphonuclear leucocyte neutral collagenolytic protease in the tear fluid of patients with corneal ulcer","volume":"61","author":"Prause, J.U.","year":"1983","unstructured":"Prause JU. Serum albumin, serum antiproteases and polymorphonuclear leucocyte neutral collagenolytic protease in the tear fluid of patients with corneal ulcer. Acta Ophthalmol (Kbh) 1983; 61: 272-82.","journal-title":"Acta Ophthalmol (Kbh)"},{"key":"ref_9","first-page":"192","article-title":"Tear and serum alpha-antitrypsin levels in corneal and conjunctival diseases","volume-title":"The preocular tear film in health, disease and contact lens wear","author":"Sen, D.K.; Sarin, G.S.","year":"1986","unstructured":"Sen DK, Sarin GS. Tear and serum alpha-antitrypsin levels in corneal and conjunctival diseases. In: Holly FJ, ed. The preocular tear film in health, disease and contact lens wear. Texas: Lubbock, Dry Eye Institute, 1986: 192-9."},{"key":"ref_10","first-page":"221","article-title":"The diagnostic and prognostic value of alpha-1 antitrypsin measurement in tear fluids","volume":"173","author":"Zirm, M.; Ritzinger, I.","year":"1978","unstructured":"Zirm M, Ritzinger I. The diagnostic and prognostic value of alpha-1 antitrypsin measurement in tear fluids. Klin Monatsbl Augenheilkd 1978; 173: 221-5.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1136\/bjo.67.3.195","article-title":"Serum and tear immunoglobulin levels in acute adenovirus conjunctivitis","volume":"67","author":"Gupta, A.K.; Sarin, G.S.","year":"1983","unstructured":"Gupta AK, Sarin GS. Serum and tear immunoglobulin levels in acute adenovirus conjunctivitis. Br J Ophthalmol 1983; 67: 195-8.","journal-title":"Br J Ophthalmol"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1136\/bjo.68.5.350","article-title":"Serum complement component depression during acute adenovirus conjunctivitis","volume":"68","author":"Gupta, A.K.; Sarin, G.S.","year":"1984","unstructured":"Gupta AK, Sarin GS. Serum complement component depression during acute adenovirus conjunctivitis. Br J Ophthalmol 1984; 68: 350-2.","journal-title":"Br J Ophthalmol"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1136\/bjo.70.6.439","article-title":"Immunoassay of tear lysozyme in acute adenovirus conjunctivitis","volume":"70","author":"Gupta, A.K.; Sarin, G.S.; Lamba, P.A.; D'Souza, P.","year":"1986","unstructured":"Gupta AK, Sarin GS, Lamba PA, D'Souza P. Immunoassay of tear lysozyme in acute adenovirus conjunctivitis. BrJ Ophthalmol 1986; 70: 439-41.","journal-title":"BrJ Ophthalmol"},{"key":"ref_14","first-page":"62","article-title":"Epidemic acute conjunctivitis in Delhi","volume":"1","author":"Gupta, A.K.; Prasad, A.K.","year":"1981","unstructured":"Gupta AK, Prasad AK. Epidemic acute conjunctivitis in Delhi (1981): a virological study. Afro-Asian J Ophthalmol 1982; 1: 62-5.","journal-title":"Afro-Asian J Ophthalmol; a virological study"},{"key":"ref_15","first-page":"136","article-title":"Virological techniques","volume":"1964","author":"Busy, D.W.G.; House, W.; MacDonald, JR","unstructured":"Busy DWG, House W, MacDonald JR. Virological techniques. London Churchill, 1964: 136.","journal-title":"London Churchill"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1099\/0022-1317-5-2-221","article-title":"The structural and functional diversity of adenovirus capsid components","volume":"5","author":"Norrby, E.","year":"1969","unstructured":"Norrby E. The structural and functional diversity of adenovirus capsid components. J Gen Virol 1969; 5: 221-36.","journal-title":"J Gen Virol"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1136\/bjo.60.4.302","article-title":"Immunoglobulin in tears of normal Indian people","volume":"60","author":"Sen, D.K.; Sarin, G.S.; Mani, K.; Saha, K.","year":"1976","unstructured":"Sen DK, Sarin GS, Mani K, Saha K. Immunoglobulin in tears of normal Indian people. Br J Ophthalmol 1976; 60: 302-4.","journal-title":"Br J Ophthalmol"},{"key":"ref_18","article-title":"A comparison of functional and immunochemical measurement of serum alpha-1 antitrypsin, in Pulmonary Emphysema and Proteolysis","volume-title":"emphysema and proteolysis","author":"Talamo, R.C.; Langley, C.E.; NE, Jr, Hyslop","year":"1972","unstructured":"Talamo RC, Langley CE, Hyslop NE Jr. A comparison of functional and immunochemical measurement of serum alpha-1 antitrypsin, in Pulmonary Emphysema and Proteolysis. In: Mittman C, ed. Pulmonary emphysema and proteolysis. New York: Academic Press, 1972."},{"key":"ref_19","first-page":"276","article-title":"Antiproteolytic activity of human serum with particular reference to its changes in the presence and consideration of its use for detection","volume-title":"of malignant neoplasia. Proc Soc Exp Biol Med 1948","volume":"69","author":"Clark, D.G.; Clifton, E.E.; Newton, B.L.","unstructured":"Clark DG, Clifton EE, Newton BL. Antiproteolytic activity of human serum with particular reference to its changes in the presence and consideration of its use for detection of malignant neoplasia. Proc Soc Exp Biol Med 1948; 69: 276-83."},{"key":"ref_20","first-page":"57","article-title":"Studies on the determination of fibrinogen in human blood plasma in studies on trypsin and plasmin inhibitors in human blood serum","volume":"14","author":"Jacobsson, K.","year":"1955","unstructured":"Jacobsson K. Studies on the determination of fibrinogen in human blood plasma in studies on trypsin and plasmin inhibitors in human blood serum. ScandJ Clin Lab Invest 1955; 14 (suppl): 57-102.","journal-title":"ScandJ Clin Lab Invest"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"483","DOI":"10.3109\/00365516309079776","article-title":"Relationship between serum concentration and urinary output of trypsin inhibitor after cortisone administration","volume":"15","author":"Faarvang, H.J.; Lauritsen, O.S.","year":"1963","unstructured":"Faarvang HJ, Lauritsen OS. Relationship between serum concentration and urinary output of trypsin inhibitor after cortisone administration. Scand J Clin Lab Invest 1963; 15: 483-90.","journal-title":"Scand J Clin Lab Invest"},{"key":"ref_22","first-page":"278","article-title":"Quantitative immunological determination of alpha-1 acid glycoprotein and alpha-1 antitrypsin in the sera of patients with rheumatoid arthritis","volume":"25","author":"Cleve, H.; Behrend, T.","year":"1966","unstructured":"Cleve H, Behrend T. Quantitative immunological determination of alpha-1 acid glycoprotein and alpha-1 antitrypsin in the sera of patients with rheumatoid arthritis. Z Rheumatol 1966; 25: 278-83.","journal-title":"Z Rheumatol"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3109\/00016346709158192","article-title":"Alpha-1 antitrypsin and alpha-2 macroglobulin concentration in serum during pregnancy","volume":"46","author":"Ganrot, P.O.; Bjerre, B.","year":"1967","unstructured":"Ganrot PO, Bjerre B. Alpha-1 antitrypsin and alpha-2 macroglobulin concentration in serum during pregnancy. Acta Obstet Gynecol Scand 1967; 46: 126-37.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref_24","first-page":"91","article-title":"Alpha-1 antitrypsin in cervical mucus","volume-title":"Fertil Steril","volume":"19","author":"Schumacher, G.F.B.; Pearl, M.J.","year":"1968","unstructured":"Schumacher GFB, Pearl MJ. Alpha-1 antitrypsin in cervical mucus. Fertil Steril 1968; 19: 91-9."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1378\/chest.64.1.39","article-title":"RL Jr. Apha-1 antitrypsin level in sarcoidosis: relationship to disease activity","volume":"64","author":"C, Jr, Young","year":"1973","unstructured":"Young C Jr, Headings VE, Bose S, Harden KA, Crockett ED Jr, Hackney RL Jr. Apha-1 antitrypsin level in sarcoidosis: relationship to disease activity. Chest 1973; 64: 39-45.","journal-title":"Chest"},{"key":"ref_26","first-page":"136","article-title":"Serum alpha-1 antitrypsin in various forms of leprosy","volume":"68","author":"Agarwal, S.K.; Saha, K.","year":"1978","unstructured":"Agarwal SK, Saha K. Serum alpha-1 antitrypsin in various forms of leprosy. Ind J Med Res 1978; 68: 136-9.","journal-title":"Ind J Med Res"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1136\/bjo.68.4.242","article-title":"Immunoassay of serum alpha-1 antitrypsin level in uveitis","volume":"68","author":"Gupta, A.K.; Sarin, G.S.","year":"1984","unstructured":"Gupta AK, Sarin GS. Immunoassay of serum alpha-1 antitrypsin level in uveitis. Br J Ophthalmol 1984; 68: 242-4.","journal-title":"Br J Ophthalmol"},{"key":"ref_28","first-page":"140","article-title":"Alpha-1 antitrypsin deficiency and liver diseases","volume-title":"Modern trends in gastroenterology","author":"Sharp, H.L.","year":"1975","unstructured":"Sharp HL. Alpha-1 antitrypsin deficiency and liver diseases. In: Read AE, ed. Modern trends in gastroenterology. 5th ed. London: Butterworths, 1975: 140.","edition":"5th ed"},{"key":"ref_29","first-page":"34","article-title":"Differentiation of leucocyte fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors","volume":"27","author":"Herman, G.; Miesscher, P.A.","year":"1965","unstructured":"Herman G, Miesscher PA. Differentiation of leucocyte fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors. IntArch Allergy 1965; 27: 34-41.","journal-title":"IntArch Allergy"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/00365517109086904","article-title":"Interaction between human or dog leucocyte proteases and plasma protease inhibitors","volume":"28","author":"Ohlsson, K.","year":"1971","unstructured":"Ohlsson K. Interaction between human or dog leucocyte proteases and plasma protease inhibitors. Scand J Clin Lab Invest 1971; 28: 225-30.","journal-title":"Scand J Clin Lab Invest"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T05:32:40Z","timestamp":1684042360000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjo.72.5.390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,5,1]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1988,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/bjo.72.5.390","relation":{},"ISSN":["0007-1161"],"issn-type":[{"value":"0007-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1988,5,1]]}}}