{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:06:24Z","timestamp":1772769984282,"version":"3.50.1"},"reference-count":15,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1989,6,1]]},"DOI":"10.1136\/bjo.73.6.427","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"427-431","source":"Crossref","is-referenced-by-count":52,"title":["Ocular complications in homocystinuria--early and late treated."],"prefix":"10.1136","volume":"73","author":[{"given":"J. P.","family":"Burke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"O'Keefe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bowell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. R.","family":"Naughten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"issue":"37","key":"ref_1","first-page":"505","article-title":"Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland","volume":"1962","author":"DN, Carson N.A.J.Neill","unstructured":"Carson NAJ. Neill DN. Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland. Arch Dis Child 1962: 37: 505-13.","journal-title":"Arch Dis Child"},{"issue":"9","key":"ref_2","first-page":"493","article-title":"The identification of homocystine in the urine","volume":"1962","author":"JG, Gerritsen T.Vaughn; HA, Waisman","unstructured":"Gerritsen T. Vaughn JG, Waisman HA. The identification of homocystine in the urine. Biochem Biophys Res Common 1962: 9: 493-6.","journal-title":"Biochem Biophys Res Common"},{"key":"ref_3","first-page":"522","article-title":"Mudd SH, Levy HL. Disorders of transulfuration","volume-title":"The metabolic basis of inherited disease","author":"Stanbury, J.B.","year":"1983","unstructured":"Mudd SH, Levy HL. Disorders of transulfuration. In: Stanbury JB, Wyngaarden JB, Fredrickson DS, Goldstein JL, Brown MS, eds. The metabolic basis of inherited disease. New York: McGraw-Hill, 1983: 522-59."},{"key":"ref_4","first-page":"273","article-title":"Thalhammer 0. Frequency of inborn errors of metabolism in some representative newborn screening centres around the world: a collaborative study","volume":"30","year":"1975","unstructured":"Thalhammer 0. Frequency of inborn errors of metabolism in some representative newborn screening centres around the world: a collaborative study. Humangenetik 1975; 30: 273-86.","journal-title":"Humangenetik"},{"key":"ref_5","first-page":"1","article-title":"The natural history of homocystinuria due to cystathionine-p-synthetase deficiency","volume":"37","author":"Mudd, S.H.; Levy, Skovby F.; H.L.","year":"1985","unstructured":"Mudd SH, Skovby F. Levy HL, et al. The natural history of homocystinuria due to cystathionine-p-synthetase deficiency. Am J Hum Genet 1985; 37: 1-31.","journal-title":"Am J Hum Genet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1021\/ac60139a006","article-title":"Automatic recording apparatus for use in the chromatography of amino acids","volume":"30","author":"Spackman, D.H.; Stein, W.I.-I.; Moor, S.","year":"1958","unstructured":"Spackman DH, Stein WI-I, Moor S. Automatic recording apparatus for use in the chromatography of amino acids. Anti Chem 1958;30: 1190-200.","journal-title":"Anti Chem"},{"issue":"7-1","key":"ref_7","first-page":"1","article-title":"Collagen profile in various clinical conditions","volume":"7","author":"Harris, E.D.; Sjoerdsma, A.","year":"1966","unstructured":"Harris ED, Sjoerdsma A. Collagen profile in various clinical conditions. Lancet 1966; ii: 7(7-1 1.","journal-title":"Lancet"},{"key":"ref_8","first-page":"21","article-title":"Ocular pathology in homocystinuria. Trais Ophthalmol Soc UK 1965; 85","author":"N, Henkind P.Ashton","unstructured":"Henkind P. Ashton N. Ocular pathology in homocystinuria. Trais Ophthalmol Soc UK 1965; 85: 21-38."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0039-6257(82)90069-8","article-title":"Ectopia lentis","volume":"27","author":"Nelson, L.B.; Maumenee, I.H.","year":"1982","unstructured":"Nelson LB, Maumenee IH. Ectopia lentis. Surv Ophthalmol 1982; 27: 143-60.","journal-title":"Surv Ophthalmol"},{"key":"ref_10","first-page":"40520","article-title":"Ocular manifestations in the Marfan syndrome and homocystinuria","volume":"75","author":"Cross, E.C.; Jensen, A.D.","year":"1973","unstructured":"Cross EC, Jensen AD. Ocular manifestations in the Marfan syndrome and homocystinuria. Am J Ophthalmol 1973; 75: 40520.","journal-title":"Am J Ophthalmol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1136\/adc.53.3.242","article-title":"Homocystinuria in New South Wales","volume":"53","author":"G, Wilcken B.Turner","year":"1978","unstructured":"Wilcken B. Turner G. Homocystinuria in New South Wales. Arch Dis Child 1978; 53: 242-5.","journal-title":"Arch Dis Child"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1177\/014107688808100517","article-title":"The eye and inherited metabolic disease: a review","volume":"81","author":"Michalski, A.; Leonard, J.V.; Taylor, D.S.I.","year":"1988","unstructured":"Michalski A, Leonard JV, Taylor DSI. The eye and inherited metabolic disease: a review. J R Soc Med 1988; 81: 286-90).","journal-title":"J R Soc Med"},{"key":"ref_13","article-title":"Homocystinuria 'homozygosity versus heterozygosity'. MD thesis. DRUK, LCG Printing BV","author":"Boers, G.H.H.","year":"1985","unstructured":"Boers GHH, Homocystinuria 'homozygosity versus heterozygosity'. MD thesis. DRUK, LCG Printing BV, Dordrecht, 1985."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0002-9394(72)90895-1","article-title":"The ocular histopathology of homocystinuria","volume":"74","author":"Ramsay, M.S.; Yanoff, M.; Fine, B.S.","year":"1972","unstructured":"Ramsay MS, Yanoff M, Fine BS. The ocular histopathology of homocystinuria. Am J Ophthalmol 1972; 74: 377-85.","journal-title":"Am J Ophthalmol"},{"issue":"26","key":"ref_15","first-page":"8","article-title":"Degenerative diseases of the peripheral retina","volume-title":"Clinical ophthalmology","volume":"3","author":"Straatsma, B.R.; Foos, R.B.; Femam, S.S.","year":"1978","unstructured":"Straatsma BR, Foos RB, Femam SS. Degenerative diseases of the peripheral retina. In: Duane TD, ed. Clinical ophthalmology. Hagerstown: Harper and Row, 1978; 3: chap. 26: 8-10."}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bjo.73.6.427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T23:13:33Z","timestamp":1601075613000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjo.73.6.427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6,1]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1989,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/bjo.73.6.427","relation":{},"ISSN":["0007-1161"],"issn-type":[{"value":"0007-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1989,6,1]]}}}