{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:46:50Z","timestamp":1791960410178,"version":"4.3.4"},"reference-count":17,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1990,6,1]]},"DOI":"10.1136\/bjo.74.6.353","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"353-357","source":"Crossref","is-referenced-by-count":85,"title":["High-dose short-term chlorambucil for intractable sympathetic ophthalmia and Behcet's disease."],"prefix":"10.1136","volume":"74","author":[{"given":"H H","family":"Tessler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Jennings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1001\/archopht.1970.00990040448008","article-title":"Treatment of Behcet's disease with chlorambucil","volume":"84","author":"Mamo, J.G.; Azzam, S.A.","year":"1970","unstructured":"Mamo JG, Azzam SA. Treatment of Behcet's disease with chlorambucil. Arch Ophthalmol 1970; 84: 446-50.","journal-title":"Arch Ophthalmol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0002-9394(74)90229-3","article-title":"The use of chlorambucil in intractable idiopathic uveitis","volume":"78","author":"Godfrey, W.A.; Epstein, W.V.; O'Connor, G.R.; Kimura, S.J.; Hogan, M.J.; Nozik, R.A.","year":"1974","unstructured":"Godfrey WA, Epstein WV, O'Connor GR, Kimura SJ, Hogan MJ, Nozik RA. The use of chlorambucil in intractable idiopathic uveitis. AmJ Ophthalmol 1974; 78: 415-28.","journal-title":"AmJ Ophthalmol"},{"key":"ref_3","first-page":"26477","article-title":"Behcet's syndrome: Treatment with chlorabucil","volume":"82","author":"Elliott, S.H.; Ballinger, W.H.","year":"1984","unstructured":"Elliott SH, Ballinger WH. Behcet's syndrome: Treatment with chlorabucil. Trans Am Ophthalmol Soc 1984; 82: 26477.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1001\/archopht.1976.03910030274004","article-title":"Treatment of Behcet's disease with chlorambucil. A follow-up report","volume":"94","author":"Mamo, J.G.","year":"1976","unstructured":"Mamo JG. Treatment of Behcet's disease with chlorambucil. A follow-up report. Arch Ophthalmol 1976; 94: 580-3.","journal-title":"Arch Ophthalmol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1056\/NEJM198004243021709","article-title":"Chlorambucil for childhood nephrosis. A word of caution","volume":"302","author":"Lewis, E.J.","year":"1980","unstructured":"Lewis EJ. Chlorambucil for childhood nephrosis. A word of caution. N Engl. Med 1980; 302: %3-4.","journal-title":"N Engl. Med"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1056\/NEJM198004243021701","article-title":"Longterm evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood","volume":"302","author":"Williams, S.A.; Makker, S.P.; Ingelfinger, JR, Grupe; W.E.","year":"1980","unstructured":"Williams SA, Makker SP, Ingelfinger JR, Grupe WE. Longterm evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood. N EnglJ Med 1980; 302: 929-33.","journal-title":"N EnglJ Med"},{"issue":"4","key":"ref_7","article-title":"International Agency for Research on Cancer","volume":"1982","unstructured":"International Agency for Research on Cancer. IARC Monogr Ogryzlo Eval CarginogRisk Chem Hum 1982: suppl 4.","journal-title":"IARC Monogr Ogryzlo Eval CarginogRisk Chem Hum"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1056\/NEJM198102193040801","article-title":"Increased incidence of acute leukemia in polycythemia vera associated Chlorambucil Behcet's with chiorambucil therapy","volume":"304","author":"Berk, P.D.; Goldberg, J.D.; Silverstein, M.N.","year":"1981","unstructured":"Berk PD, Goldberg JD, Silverstein MN, et al. Increased incidence of acute leukemia in polycythemia vera associated Chlorambucil Behcet's with chiorambucil therapy. NEnglJMed 1981; 304: 441-7.","journal-title":"NEnglJMed"},{"key":"ref_9","first-page":"299","article-title":"Gonadal effects of nephrotic Peduatr chlorambucil given to prepubertal and pubertal boys for syndrome","volume":"92","author":"G, Guesry Lenoir; M, Broyer","year":"1978","unstructured":"Guesry Lenoir G, Broyer M. Gonadal effects of nephrotic Peduatr chlorambucil given to prepubertal and pubertal boys for syndrome. 1978; 92: 299-303."},{"key":"ref_10","first-page":"197","article-title":"Rheumatoid arthritis treated with Medj Aust","volume":"11","author":"Thorpe, P.; Hassall, J.E.; York, JR","year":"1976","unstructured":"Thorpe P, Hassall JE, York JR. Rheumatoid arthritis treated with Medj Aust 1976; 11: 197-9."},{"key":"ref_11","first-page":"37","article-title":"The estimation of chlorambucil, phenyl acetic mustard and prednisone in human plasma by high performance liquid chromatography","volume-title":"Biological\/biomedical application of liquid chromatography","volume":"2","author":"Newell, D.R.; Hart, L.I.; Calvert, I.T.","year":"1979","unstructured":"Newell DR, Hart LI, Calvert IT, et al. The estimation of chlorambucil, phenyl acetic mustard and prednisone in human plasma by high performance liquid chromatography. In: Hawk GL,ed. Biological\/biomedical application of liquid chromatography. New York: Dekker, 1979; 2: 37-48."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"691","DOI":"10.7326\/0003-4819-87-6-691","article-title":"Wegener's granulomatosis, lymphomatoid granulomatosis and benign lymphocytic angiitis and granulomatosis of lung","volume":"87","author":"Israel, H.L.; Patchefsky, A.S.; Saldana, M.J.","year":"1977","unstructured":"Israel HL, Patchefsky AS, Saldana MJ. Wegener's granulomatosis, lymphomatoid granulomatosis and benign lymphocytic angiitis and granulomatosis of lung. Ann Intern Med Behcet's 1977; 87: 691-9.","journal-title":"Ann Intern Med Behcet's"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1056\/NEJM198212023072302","article-title":"Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer","volume":"307","author":"Greene, M.H.; Boice, J.D.; Guer, B.E.; Blessing, J.A.; Dembo, A.J.","year":"1982","unstructured":"Greene MH, Boice JD, Guer BE, Blessing JA, Dembo AJ. Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer. N Engl Med 1982; 307: 1416-21.","journal-title":"N Engl Med"},{"key":"ref_14","first-page":"67","article-title":"Acute myelononmalignant blastic leukemia after immunodepressive thereapy for primary disease","volume":"2","author":"Tchernia, G.; Mielut, F.; Subtil, E.; Parmentier, C.","year":"1976","unstructured":"Tchernia G, Mielut F, Subtil E, Parmentier C. Acute myelononmalignant blastic leukemia after immunodepressive thereapy for primary disease. Blood Cells 1976; 2: 67-80.","journal-title":"Blood Cells"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0140-6736(80)91138-1","article-title":"Acute monoblastic leukemia in child receiving chlorambucil for juvenile rheumatoid arthritis","volume":"i:","author":"Lebranchu, Y.; Drucker, J.; Nivet","year":"1980","unstructured":"Lebranchu Y, Drucker J, Nivet, et al. Acute monoblastic leukemia in child receiving chlorambucil for juvenile rheumatoid arthritis. Lancet 1980; i: 649.","journal-title":"Lancet"},{"key":"ref_16","first-page":"1065","article-title":"Chlorambucil and leukemia","volume":"2","author":"Cameron, S.","year":"1977","unstructured":"Cameron S. Chlorambucil and leukemia. N EnglJ Med 1977; 2%: 1065.","journal-title":"N EnglJ Med"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1001\/jama.1971.03190120030006","article-title":"Alkylating agents and human spermatogenesis","volume":"217","author":"Miller, D.","year":"1971","unstructured":"Miller D. Alkylating agents and human spermatogenesis. JAMA 1971; 217: 1662-5.","journal-title":"JAMA"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bjo.74.6.353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T23:15:09Z","timestamp":1601075709000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjo.74.6.353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,6,1]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1990,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/bjo.74.6.353","relation":{},"ISSN":["0007-1161"],"issn-type":[{"value":"0007-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1990,6,1]]}}}