{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:08:02Z","timestamp":1790244482311,"version":"4.1.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Ophthalmology"],"published-print":{"date-parts":[[1995,1,1]]},"DOI":"10.1136\/bjo.79.1.54","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T21:53:19Z","timestamp":1190152399000},"page":"54-56","source":"Crossref","is-referenced-by-count":57,"title":["Adverse ocular effects associated with niacin therapy."],"prefix":"10.1136","volume":"79","author":[{"given":"F W","family":"Fraunfelder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F T","family":"Fraunfelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D R","family":"Illingworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/0002-9394(73)90738-1","article-title":"Nicotinic acid maculopathy","volume":"76","author":"Gass, J.D.M.","year":"1973","unstructured":"Gass JDM. Nicotinic acid maculopathy. Am J Ophthalmol 1973; 76: 500-10.","journal-title":"Am J Ophthalmol"},{"issue":"15","key":"ref_2","first-page":"423","article-title":"Effect of nicotinic acid on blood cholesterol","volume":"1960","author":"Chazin, B.J.","unstructured":"Chazin BJ. Effect of nicotinic acid on blood cholesterol. Geriatrics 1960; 15: 423.","journal-title":"Geriatrics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/S0161-6420(88)33073-3","article-title":"Niacin maculopathy","volume":"95","year":"1988","unstructured":"Millay RH, Klein ML, Illingworth DR. Niacin maculopathy. Ophthalmology 1988; 95: 930.","journal-title":"Ophthalmology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0002-9394(63)91658-1","article-title":"Toxic amblyopia associated with administration nicotinic acid","volume":"55","author":"Harris, J.L.","year":"1963","unstructured":"Harris JL. Toxic amblyopia associated with administration nicotinic acid. Am J Ophthalmol 1963; 55: 133.","journal-title":"Am J Ophthalmol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1001\/jama.1957.02980210030009","article-title":"Reduction in elevated blood cholesterol levels by large doses of nicotinic acid","volume":"165","author":"WB, Jr, Parsons; JH, Flinn","year":"1957","unstructured":"Parsons WB Jr, Flinn JH. Reduction in elevated blood cholesterol levels by large doses of nicotinic acid. JAMA 1957; 165: 234-8.","journal-title":"JAMA"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00041433-199302000-00007","article-title":"Triglyceride lowering agents, fibrates and nicotinic acid","volume":"4","year":"1993","unstructured":"Larsen ML, Illingworth DR. Triglyceride lowering agents, fibrates and nicotinic acid. Current Opinion in Lipidology 1993; 4: 34-40.","journal-title":"Current Opinion in Lipidology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1001\/archinte.1988.00380010040006","article-title":"The Expert Panel. Report of the national cholesterol education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults","volume":"148","year":"1988","unstructured":"The Expert Panel. Report of the national cholesterol education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults. Arch Intern Med 1988; 148: 36-69.","journal-title":"Arch Intern Med"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1001\/jama.1990.03440160047035","article-title":"Prescribed use of cholesterol-lowering drugs in the United States 1978-1988","volume":"263","author":"Wysowski, D.K.; Kennedy, D.L.; Gross, T.P.","year":"1990","unstructured":"Wysowski DK, Kennedy DL, Gross TP. Prescribed use of cholesterol-lowering drugs in the United States 1978-1988.JIAMA 1990; 263: 2185-8.","journal-title":"JIAMA"},{"key":"ref_9","first-page":"1704","article-title":"Niacin maculopathy. Author's reply RH Millay","volume":"95","author":"Jampol, L.M.","year":"1988","unstructured":"Jampol LM. Niacin maculopathy. Author's reply RH Millay. Ophthalmology 1988; 95: 1704-5.","journal-title":"Ophthalmology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"815","DOI":"10.3109\/02713688409000793","article-title":"Vitamin A is present in retinol in tears of humans and rabbits","volume":"3","author":"Ubels, J.L.; MacRae, S.M.","year":"1984","unstructured":"Ubels JL, MacRae SM. Vitamin A is present in retinol in tears of humans and rabbits. Curr Eye Res 1984; 3: 815.","journal-title":"Curr Eye Res"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T10:25:20Z","timestamp":1601115920000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjo.79.1.54"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/bjo.79.1.54","relation":{},"ISSN":["0007-1161"],"issn-type":[{"value":"0007-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1995,1,1]]}}}