{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T07:03:05Z","timestamp":1776495785279,"version":"3.51.2"},"reference-count":18,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"accepted":{"date-parts":[[2016,10,9]]},"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the anatomical and functional results of vitreoretinal surgery in patients with advanced familial exudative vitreoretinopathy (FEVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of data for 10 eyes of 9 patients with advanced FEVR who underwent pars plana vitrectomy from March 1997 to May 2015 and had a follow-up of at least 12\u2005months. The primary outcomes were final visual acuity (VA) and anatomical success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age at the time of the surgery was 10.1\u00b16.5\u2005years (range 2\u2005months\u201318\u2005years). The mean follow-up period was 58.4\u00b175.1\u2005months. The male-to-female ratio was 7\/2. The mean number of vitreoretinal operations was 1.5. At the last visit, 7 (70%) eyes had complete or partial retinal attachment. Preoperatively, the mean Snellen VA was 20\/4000 (n=8), and in the remaining 2 (20%) eyes it was recorded as \u2018central, steady and maintained\u2019. At final examination, the mean Snellen VA was 20\/330 (n=7), and in the remaining 3 (30%) eyes it was recorded as light perception. At the final visit, 5 eyes (50%) had improved VA, 2 eyes (20%) showed stabilisation, and 3 eyes (30%) with total retinal detachment had a decrease in VA. No progression to glaucoma was observed and no enucleation was necessary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Advanced FEVR in young children tends to be more aggressive, leading to severe complications. These cases are challenging and require special consideration. Despite surgery, disease-related complications remain high. However, surgical intervention for advanced FEVR might be of benefit in helping to preserve vision.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bjophthalmol-2016-309526","type":"journal-article","created":{"date-parts":[[2016,10,29]],"date-time":"2016-10-29T00:58:11Z","timestamp":1477702691000},"page":"946-950","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Anatomical and functional outcomes following vitrectomy for advanced familial exudative vitreoretinopathy: a single surgeon's experience"],"prefix":"10.1136","volume":"101","author":[{"given":"Mumin","family":"Hocaoglu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Karacorlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isil","family":"Sayman Muslubas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Giray","family":"Ersoz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serra","family":"Arf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,10,28]]},"reference":[{"key":"2024092603303466000_101.7.946.1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(69)91237-9"},{"key":"2024092603303466000_101.7.946.2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2014.70"},{"key":"2024092603303466000_101.7.946.3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1220864110"},{"key":"2024092603303466000_101.7.946.4","doi-asserted-by":"publisher","DOI":"10.1086\/383202"},{"key":"2024092603303466000_101.7.946.5","first-page":"705","article-title":"Genotype-phenotype variations in five Spanish families with Norrie disease or X-linked FEVR","volume":"11","author":"Riveiro-Alvarez","year":"2005","journal-title":"Mol Vis"},{"key":"2024092603303466000_101.7.946.6","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970317)69:2<217::AID-AJMG19>3.0.CO;2-O"},{"key":"2024092603303466000_101.7.946.7","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000830"},{"key":"2024092603303466000_101.7.946.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.06.002"},{"key":"2024092603303466000_101.7.946.9","first-page":"323","article-title":"Familial exudative vitreoretinopathy (FEVR). Clinical profile and management","volume":"51","author":"Shukla","year":"2003","journal-title":"Indian J Ophthalmol"},{"key":"2024092603303466000_101.7.946.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.06.020"},{"key":"2024092603303466000_101.7.946.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)96002-X"},{"key":"2024092603303466000_101.7.946.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90268-3"},{"key":"2024092603303466000_101.7.946.13","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200604000-00005"},{"key":"2024092603303466000_101.7.946.14","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31821c3ec5"},{"key":"2024092603303466000_101.7.946.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.08.009"},{"key":"2024092603303466000_101.7.946.16","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000961"},{"key":"2024092603303466000_101.7.946.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)76893-X"},{"key":"2024092603303466000_101.7.946.18","doi-asserted-by":"publisher","DOI":"10.1080\/08820530902800108"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bjophthalmol-2016-309526","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T10:31:31Z","timestamp":1727346691000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjophthalmol-2016-309526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,28]]},"references-count":18,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2017,6,26]]},"published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1136\/bjophthalmol-2016-309526"],"URL":"https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309526","relation":{},"ISSN":["0007-1161","1468-2079"],"issn-type":[{"value":"0007-1161","type":"print"},{"value":"1468-2079","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,28]]}}}