{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:30:44Z","timestamp":1792643444286,"version":"4.5.0"},"reference-count":27,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Ophthalmol"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1136\/bjophthalmol-2016-309729","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T02:33:44Z","timestamp":1484966024000},"page":"1185-1192","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":55,"title":["Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report"],"prefix":"10.1136","volume":"101","author":[{"given":"Nichole","family":"Joachim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna Maria","family":"Colijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Kifley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine E","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6212-9403","authenticated-orcid":false,"given":"Gabri\u00eblle H S","family":"Buitendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E K","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chelsea E","family":"Myers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy M","family":"Meuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ava G","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth G","family":"Holliday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Attia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Liew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha K","family":"Iyengar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulus T V M","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Hofman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes R","family":"Vingerling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline C W","family":"Klaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,1,20]]},"reference":[{"key":"key-10.1136\/bjophthalmol-2016-309729-1","first-page":"844","article-title":"Global data on visual impairment in the year 2002","volume":"82","author":"Resnikoff","year":"2004","journal-title":"Bull World Health Organ"},{"key":"key-10.1136\/bjophthalmol-2016-309729-2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2415-15-9","article-title":"Evaluation of real-world mobility in age-related macular degeneration","volume":"15","author":"Sengupta","year":"2015","journal-title":"BMC Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ophtha.2004.06.036","article-title":"Vision-related quality of life in patients with bilateral severe age-related macular degeneration","volume":"112","author":"Cahill","year":"2005","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-4","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/S0161-6420(02)01055-2","article-title":"Five-year incidence of age-related maculopathy lesions: the Blue Mountains Eye Study","volume":"109","author":"Mitchell","year":"2002","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-5","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.ophtha.2006.07.017","article-title":"Ten-year incidence and progression of age-related maculopathy: the blue Mountains Eye Study","volume":"114","author":"Wang","year":"2007","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0161-6420(97)30368-6","article-title":"The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study","volume":"104","author":"Klein","year":"1997","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-7","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/S0161-6420(02)01146-6","article-title":"Ten-year incidence and progression of age-related maculopathy: the Beaver Dam eye study","volume":"109","author":"Klein","year":"2002","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-8","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1001\/archopht.121.4.519","article-title":"The risk and natural course of age-related maculopathy: follow-up at 6 \u00bd years in the Rotterdam study","volume":"121","author":"van Leeuwen","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-9","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1001\/archopht.1993.01090090041018","article-title":"Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Macular Photocoagulation Study Group","volume":"111","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-10","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1001\/jamaophthalmol.2014.4252","article-title":"Severity of age-related macular degeneration in 1 eye and the incidence and progression of age-related macular degeneration in the fellow eye: the beaver dam eye study","volume":"133","author":"Gangnon","year":"2015","journal-title":"JAMA Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3109\/09286586.2013.867512","article-title":"Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium","volume":"21","author":"Klein","year":"2014","journal-title":"Ophthalmic Epidemiol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-12","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ajo.2014.05.027","article-title":"Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium","volume":"158","author":"Klein","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-13","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/S0161-6420(95)30846-9","article-title":"Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study","volume":"102","author":"Mitchell","year":"1995","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-14","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0161-6420(92)31871-8","article-title":"Prevalence of age-related maculopathy. The Beaver Dam Eye Study","volume":"99","author":"Klein","year":"1992","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-15","first-page":"2237","article-title":"Incidence and progression rates of age-related maculopathy: the Rotterdam Study","volume":"42","author":"Klaver","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key-10.1136\/bjophthalmol-2016-309729-16","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/S0161-6420(91)32186-9","article-title":"The Wisconsin age-related maculopathy grading system","volume":"98","author":"Klein","year":"1991","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-17","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.ophtha.2013.10.017","article-title":"Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations","volume":"121","author":"Wang","year":"2014","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-18","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/aje\/kwf092","article-title":"Ten-year incidence of age-related maculopathy and smoking and drinking: the Beaver Dam Eye Study","volume":"156","author":"Klein","year":"2002","journal-title":"Am J Epidemiol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-19","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1001\/archopht.1996.01100140393005","article-title":"Age-related macular degeneration and smoking. The Rotterdam Study","volume":"114","author":"Vingerling","year":"1996","journal-title":"Arch Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-20","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.ophtha.2003.11.010","article-title":"Risk factors for incident age-related macular degeneration: pooled findings from 3 continents","volume":"111","author":"Tomany","year":"2004","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-21","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/aje\/kwn358","article-title":"Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort","volume":"169","author":"Wang","year":"2009","journal-title":"Am J Epidemiol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-22","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1001\/jamaophthalmol.2013.713","article-title":"Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study","volume":"131","author":"Klein","year":"2013","journal-title":"JAMA Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-23","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1016\/j.ophtha.2013.07.053","article-title":"Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium","volume":"120","author":"Buitendijk","year":"2013","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-24","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.ophtha.2010.07.009","article-title":"Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration","volume":"117","author":"Reynolds","year":"2010","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-25","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.ajo.2003.09.015","article-title":"Cholesterol and age-related macular degeneration: is there a link?","volume":"137","author":"van Leeuwen","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"key-10.1136\/bjophthalmol-2016-309729-26","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1016\/j.ophtha.2011.04.029","article-title":"Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors","volume":"118","author":"Seddon","year":"2011","journal-title":"Ophthalmology"},{"key":"key-10.1136\/bjophthalmol-2016-309729-27","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ophtha.2014.10.012","article-title":"Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test?","volume":"122","author":"Chew","year":"2015","journal-title":"Ophthalmology"}],"container-title":["British Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bjophthalmol-2016-309729","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T08:54:13Z","timestamp":1601110453000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjo.bmj.com\/lookup\/doi\/10.1136\/bjophthalmol-2016-309729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,20]]},"references-count":27,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,8,23]]},"published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1136\/bjophthalmol-2016-309729"],"URL":"https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309729","relation":{},"ISSN":["0007-1161","1468-2079"],"issn-type":[{"value":"0007-1161","type":"print"},{"value":"1468-2079","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,20]]}}}